A concise approach to 2-azabicyclo[3.3.1]nonane derivatives from an acyclic precursor

被引：16

作者：

Aurrecoechea, JM ^{[1
]}

Gorgojo, JM ^{[1
]}

Saornil, C ^{[1
]}

机构：

[1] Univ Basque Country, Fac Ciencias & Tecnol, Dept Quim Organ 2, Bilbao 48080, Spain

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 23期

关键词：

D O I：

10.1021/jo051471c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Condensation of a readily available 5-amino-2-alkenoate ester with alpha-unsubstituted aliphatic aldehydes leads to substituted 1,2,3,4-tetrahydropyridines. Subsequent manipulation of the ester and enamine functions gives a quick access to 2-azabicyclo[3.3.1]nonane-containing compounds.

引用

页码：9640 / 9643

页数：4

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