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Regioselective syntheses of fully-substituted 1,2,3-triazoles: the CuAAC/C-H bond functionalization nexus

被引：220
作者：
Ackermann, Lutz [1 ]
Potukuchi, Harish Kumar [1 ]
机构：
[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2010年 / 8卷 / 20期
关键词：
PALLADIUM-CATALYZED ARYLATION; AZIDE-ALKYNE CYCLOADDITION; MEDIATED DIRECT ARYLATION; CROSS-COUPLING REACTIONS; C-H; CARBON-HYDROGEN; CLICK CHEMISTRY; ARYL CHLORIDES; 1,3-DIPOLAR CYCLOADDITIONS; DIRECT ALKYNYLATION;
D O I：
10.1039/c0ob00212g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Regioselective syntheses of 1,4,5-trisubstituted 1,2,3- triazoles were accomplished by three different strategies, relying on (i) the interception of stoichiometrically formed 5-cuprated-1,2,3-triazoles, (ii) the use of stoichiometrically functionalized alkynes or (iii) catalytic C-H bond functionalizations. This perspective article summarizes progress in this research area until June 2010.
引用
收藏
页码：4503 / 4513
页数：11
相关论文
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