Nuclei Take a Position: Managing Nuclear Location

被引：119

作者：

Burke, Brian ^{[1
,2
]}

Roux, Kyle J. ^{[1
]}

机构：

[1] Univ Florida, Dept Anat & Cell Biol, Gainesville, FL 32610 USA

[2] Inst Med Biol, Singapore 138648, Singapore

来源：

DEVELOPMENTAL CELL | 2009年 / 17卷 / 05期

关键词：

KASH-DOMAIN PROTEINS; CYTOPLASMIC DYNEIN; MEMBRANE PROTEIN; LAMIN-A; ENVELOPE BREAKDOWN; MIGRATION; CENTROSOME; CELLS; ACTIN; LOCALIZATION;

D O I：

10.1016/j.devcel.2009.10.018

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Eukaryotic cells display considerable morphological plasticity linked to their abilities to carry out a myriad of complex functions. Structural rearrangements associated with cellular activities, from yeast mitosis to cell migration in the mammalian central nervous system, often involve relocation of the cell nucleus. Recent studies have provided insight into how nuclear components can be mechanically coupled to the cytoskeleton, providing a more complete understanding of the role of nuclear positioning in both health and disease.

引用

页码：587 / 597

页数：11

共 104 条

[1] Microtubule interactions with the cell cortex causing nuclear movements in Saccharomyces cerevisiae [J].

Adames, NR ;

Cooper, JA .

JOURNAL OF CELL BIOLOGY, 2000, 149 (04) :863-874

[2] THE NUCLEAR LAMINA IS A MESHWORK OF INTERMEDIATE-TYPE FILAMENTS [J].

AEBI, U ;

COHN, J ;

BUHLE, L ;

GERACE, L .

NATURE, 1986, 323 (6088) :560-564

[3] Syne-1, a dystrophin- and klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction [J].

Apel, ED ;

Lewis, RM ;

Grady, RM ;

Sanes, JR .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (41) :31986-31995

[4] THE SUBCELLULAR ORGANIZATION OF MADIN-DARBY CANINE KIDNEY-CELLS DURING THE FORMATION OF A POLARIZED EPITHELIUM [J].

BACALLAO, R ;

ANTONY, C ;

DOTTI, C ;

KARSENTI, E ;

STELZER, EHK ;

SIMONS, K .

JOURNAL OF CELL BIOLOGY, 1989, 109 (06) :2817-2832

[5] Nuclear migration during retinal development [J].

Baye, Lisa M. ;

Link, Brian A. .

BRAIN RESEARCH, 2008, 1192 :29-36

[6] Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina [J].

Beaudouin, J ;

Gerlich, D ;

Daigle, N ;

Eils, R ;

Ellenberg, J .

CELL, 2002, 108 (01) :83-96

[7] Nucleokinesis in tangentially migrating neurons comprises two alternating phases:: Forward migration of the Golgi/centrosome associated with centrosome splitting and myosin contraction at the rear [J].

Bellion, A ;

Baudoin, JP ;

Alvarez, C ;

Bornens, M ;

Métin, C .

JOURNAL OF NEUROSCIENCE, 2005, 25 (24) :5691-5699

[8] TorsinA: Movement at many levels [J].

Breakefield, XO ;

Kamm, C ;

Hanson, PI .

NEURON, 2001, 31 (01) :9-12

[9] Decreased mechanical stiffness in LMNA-/- cells is caused by defective nucleo-cytoskeletal integrity: implications for the development of laminopathies [J].

Broers, JLV ;

Peeters, EAG ;

Kuijpers, HJH ;

Endert, J ;

Bouten, CVC ;

Oomens, CWJ ;

Baaijens, FPT ;

Ramaekers, FCS .

HUMAN MOLECULAR GENETICS, 2004, 13 (21) :2567-2580

[10] Histone acetyltransferase hALP and nuclear membrane protein hsSUN1 function in de-condensation of mitotic chromosomes [J].

Chi, Ya-Hui ;

Haller, Kerstin ;

Peloponese, Jean-Marie, Jr. ;

Jeang, Kuan-Teh .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (37) :27447-27458

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