Gold and iron oxide hybrid nanocomposite materials

被引:225
作者
Leung, Ken Cham-Fai [1 ,2 ,3 ]
Xuan, Shouhu [3 ,4 ]
Zhu, Xiaoming [3 ]
Wang, Dawei [3 ]
Chak, Chun-Pong [3 ]
Lee, Siu-Fung [3 ]
Ho, Watson K. -W. [3 ]
Chung, Berton C. -T. [3 ]
机构
[1] Hong Kong Baptist Univ, Inst Creat, Kowloon, Hong Kong, Peoples R China
[2] Hong Kong Baptist Univ, Dept Chem, Kowloon, Hong Kong, Peoples R China
[3] Chinese Univ Hong Kong, Dept Chem, Inst Mol Funct Mat, Ctr Novel Funct Mol, Shatin, Hong Kong, Peoples R China
[4] Univ Sci & Technol China, Dept Modern Mech, CAS Key Lab Mech Behav & Design Mat, Hefei 230026, Peoples R China
关键词
TARGETING GENE DELIVERY; OPTICAL-PROPERTIES; NANOPARTICLE PROBES; AU-FE3O4; NANOPARTICLES; MAGNETIC NANOPARTICLES; CONTRAST AGENT; DRUG-DELIVERY; CANCER; CORE; PURIFICATION;
D O I
10.1039/c1cs15213k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This critical review provides an overview of current research activities that focused on the synthesis and application of multi-functional gold and iron oxide (Au-FexOy) hybrid nanoparticles and nanocomposites. An introduction of synthetic strategies that have been developed for generating Au-FexOy nanocomposites with different nanostructures is presented. Surface functionalisation and bioconjugation of these hybrid nanoparticles and nanocomposites are also reviewed. A variety of applications such as theranostics, gene delivery, biosensing, cell sorting, bio-separation, and catalysis is discussed and highlighted. Finally, future trends and perspectives of these sophisticated nanocomposites are outlined. Underpinning the fundamental requirements for effectively forming Au-FexOy hybrid nanocomposite materials would shed light on future development of nanotheranostics, nanomedicines, and chemical technologies. It would be interesting to investigate such multi-component composite nanomaterials with different novel morphologies in the near future to advance chemistry, biology, medicine, and engineering multi-disciplinary research (120 references).
引用
收藏
页码:1911 / 1928
页数:18
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