Peptidoglycan and muropeptides from pathogens Agrobacterium and Xanthomonas elicit plant innate immunity:: Structure and activity

被引:111
作者
Erbs, Gitte [2 ]
Silipo, Alba [1 ]
Aslam, Shazia [3 ]
De Castro, Cristina [1 ]
Liparoti, Valeria [1 ]
Flagiello, Angela [4 ]
Pucci, Pietro [1 ,4 ]
Lanzetta, Rosa [1 ]
Parrilli, Michelangelo [1 ]
Molinaro, Antonio [1 ]
Newman, Mari-Anne [2 ]
Cooper, Richard M. [3 ]
机构
[1] Univ Naples Federico II, Dipartimento Chim Organ & Biochim, I-80126 Naples, Italy
[2] Univ Copenhagen, Fac Life Sci, Dept Plant Biol, DK-1871 Frederiksberg, Denmark
[3] Univ Bath, Dept Biol & Biochem, Bath BA2 7AY, Avon, England
[4] CEINGE Biotecnol Avanzate, I-80145 Naples, Italy
来源
CHEMISTRY & BIOLOGY | 2008年 / 15卷 / 05期
关键词
D O I
10.1016/j.chembiol.2008.03.017
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Peptidoglycan (PGN) is a unique and essential structural part of the bacterial cell wall. PGNs from two contrasting Gram-negative plant pathogenic bacteria elicited components characteristic of the innate immune system in Arabidopsis thaliana, such as transcription of the defense gene PR1, oxidative burst, medium alkalinization, and formation of callose. Highly purified muropeptides from PGNs were more effective elicitors of early defense responses than native PGN. Therefore, PGN and its constituents represent a Microbe-Associated Molecular Pattern (MAMP) in plant-bacterial interactions. PGN and muropeptides from aggressive Xanthomonas campestris pv. campestris were significantly more active than those from Agrobacterium tumefaciens, which must maintain host cell viability during infection. The structure of muropeptide components and the distinctive differences are described. Differing defense-eliciting abilities appear to depend on subtle structural differences in either carbohydrate or peptide groups.
引用
收藏
页码:438 / 448
页数:11
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