Chemical Modification of Oligonucleotides for Therapeutic, Bioanalytical and other Applications

被引：91

作者：

Bell, Neil M. ^{[1
]}

Micklefield, Jason ^{[1
]}

机构：

[1] Univ Manchester, Sch Chem, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England

来源：

CHEMBIOCHEM | 2009年 / 10卷 / 17期

关键词：

antisense agents; conjugation; nucleic acids; oligonucleotides; RNAi; PEPTIDE NUCLEIC-ACIDS; RNA-INTERFERENCE; ANTISENSE OLIGONUCLEOTIDES; ANTIVIRAL ACTIVITY; DNA; INHIBITION; EXPRESSION; PNA; DESIGN; MICE;

D O I：

10.1002/cbic.200900341

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：2691 / 2703

页数：13

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