Impact of inlet channel geometry on microfluidic drop formation

被引:111
作者
Abate, A. R. [1 ,2 ]
Poitzsch, A. [3 ]
Hwang, Y. [4 ]
Lee, J. [5 ]
Czerwinska, J. [6 ]
Weitz, D. A. [1 ,2 ]
机构
[1] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
[2] Harvard Univ, SEAS, Cambridge, MA 02138 USA
[3] Pinkerton Acad, Derry, NH 03038 USA
[4] St Pauls Sch, Concord, NH 03301 USA
[5] Lexington High Sch, Lexington, MA 02421 USA
[6] Polish Acad Sci, IPPT PAN, PL-00049 Warsaw, Poland
来源
PHYSICAL REVIEW E | 2009年 / 80卷 / 02期
基金
美国国家科学基金会;
关键词
drops; emulsions; microfluidics; pipe flow; ON-A-CHIP; JANUS PARTICLES; SINGLE-CELLS; FABRICATION; ENCAPSULATION; BUBBLES; PHYSICS; SHELLS;
D O I
10.1103/PhysRevE.80.026310
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 [等离子体物理]; 070301 [无机化学];
摘要
We study the impact of inlet channel geometry on microfluidic drop formation. We show that drop makers with T-junction style inlets form monodisperse emulsions at low and moderate capillary numbers and those with Flow-Focus style inlets do so at moderate and high capillary numbers. At low and moderate capillary number, drop formation is dominated by interfacial forces and mediated by the confinement of the microchannels; drop size as a function of flow-rate ratio follows a simple functional form based on a blocking-squeezing mechanism. We summarize the stability of the drop makers with different inlet channel geometry in the form of a phase diagram as a function of capillary number and flow-rate ratio.
引用
收藏
页数:5
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