Quantitative retinal-blood flow measurement with three-dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography

被引：94

作者：

Makita, Shuichi ^{[1
]}

Fabritius, Tapio ^{[1
]}

Yasuno, Yoshiaki ^{[1
]}

机构：

[1] Univ Tsukuba, Computat Opt Grp, Tsukuba, Ibaraki 3058573, Japan

来源：

OPTICS LETTERS | 2008年 / 33卷 / 08期

关键词：

D O I：

10.1364/OL.33.000836

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Retinal blood flow quantification by retinal vessel segmentation with Doppler optical coherence angiography is presented. Vessel diameter, orientation, and position are determined in an en face vessel image and two representative cross-sectional flow images of the vessel. Absolute blood flow velocity is calculated with the help of the measured Doppler frequency shift and determined vessel angle. The volumetric flow rate is obtained with the position and the region of the vessel lumen. The volumetric blood flow rate of retinal arteries before and after a bifurcation is verified in a healthy human eye. (C) 2008 Optical Society of America.

引用

收藏

页码：836 / 838

页数：3

相关论文

共 13 条

[1] Quantification of a three-dimensional velocity vector using spectral-domain Doppler optical coherence tomography [J].

Ahn, Yeh-Chan ;

Jung, Woonggyu ;

Chen, Zhongping .

OPTICS LETTERS, 2007, 32 (11) :1587-1589

[2] Resonant Doppler flow imaging and optical vivisection of retinal blood vessels [J].

Bachmann, Adrian H. ;

Villiger, Martin L. ;

Blatter, Cedric ;

Lasser, Theo ;

Leitgeb, Rainer A. .

OPTICS EXPRESS, 2007, 15 (02) :408-422

[3] ROBUST 2-DIMENSIONAL WEIGHTED AND UNWEIGHTED PHASE UNWRAPPING THAT USES FAST TRANSFORMS AND ITERATIVE METHODS [J].

GHIGLIA, DC ;

ROMERO, LA .

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1994, 11 (01) :107-117

[4] Three-dimensional visualization of choroidal vessels by using standard and ultra-high resolution scattering optical coherence angiography [J].

Hong, Youngjoo ;

Makita, Shuichi ;

Yamanari, Masahiro ;

Miura, Masahiro ;

Kim, Soohyun ;

Yatagai, Toyohiko ;

Yasuno, Yoshiaki .

OPTICS EXPRESS, 2007, 15 (12) :7538-7550

[5]

KOLLER TM, 1995, FIFTH INTERNATIONAL CONFERENCE ON COMPUTER VISION, PROCEEDINGS, P864, DOI 10.1109/ICCV.1995.466846

[6] Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography [J].

Leitgeb, RA ;

Schmetterer, L ;

Drexler, W ;

Fercher, AF ;

Zawadzki, RJ ;

Bajraszewski, T .

OPTICS EXPRESS, 2003, 11 (23) :3116-3121

[7] Optical coherence angiography [J].

Makita, Shuichi ;

Hong, Youngjoo ;

Yamanari, Masahiro ;

Yatagai, Toyohiko ;

Yasuno, Yoshiaki .

OPTICS EXPRESS, 2006, 14 (17) :7821-7840

[8] Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography [J].

Michaely, Roland ;

Bachmann, Adrian H. ;

Villiger, Martin L. ;

Blatter, Cedric ;

Lasser, Theo ;

Leitgeb, Rainer A. .

JOURNAL OF BIOMEDICAL OPTICS, 2007, 12 (04)

[9] Measurement of absolute flow velocity vector using dual-angle, delay-encoded Doppler optical coherence tomography [J].

Pedersen, Cameron J. ;

Huang, David ;

Shure, Mark A. ;

Rollins, Andrew M. .

OPTICS LETTERS, 2007, 32 (05) :506-508

[10] Quantifying Doppler angle and mapping flow velocity by a combination of Doppler-shift and Doppler-bandwidth measurements in optical Doppler tomography [J].

Piao, DQ ;

Zhu, Q .

APPLIED OPTICS, 2003, 42 (25) :5158-5166