Autonomously-triggered microfluidic cooling using thermo-responsive hydrogels

被引:34
作者
Agarwal, Abhishek K.
Dong, Liang
Beebe, David J.
Jiang, Hongrui
机构
[1] Univ Wisconsin, Dept Elect & Comp Engn, Madison, WI 53706 USA
[2] Univ Wisconsin, Dept Biomed Engn, Madison, WI 53706 USA
关键词
D O I
10.1039/b617767k
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We present autonomously-triggered on-chip microfluidic cooling devices that utilize thermoresponsive hydrogels to adapt to local environmental temperatures. An external rotating magnetic stirrer couples with an in situ fabricated nickel impeller in these centrifugal-based microfluidic cooling devices to recirculate cooler water. Temperature-responsive hydrogels, which exhibit volumetric expansion and contraction, are integrated at the axle of the impeller. In this design, the hydrogels behave similar to an automotive clutch, to autonomously control the impeller's rotation as a function of the local environmental temperature. Therefore, the hydrogels act as both sensors and actuators and help take away the necessity for additional temperature sensing, feedback, and/or control units here. Cooling devices capable of on-chip thermal management at multiple predetermined onset operation points are realized by changes to the composition of hydrogel to alter its lowest critical solution temperature (LCST). Furthermore, the effect of magnetic stirrer frequency on the fluid cooling and flowrates for different two-blade nickel impeller designs are presented.
引用
收藏
页码:310 / 315
页数:6
相关论文
共 24 条
[1]   Integration of polymer and metal microstructures using liquid-phase photopolymerization [J].
Agarwal, AK ;
Beebe, DJ ;
Jiang, HR .
JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2006, 16 (02) :332-340
[2]   Programmable autonomous micromixers and micropumps [J].
Agarwal, AK ;
Sridharamurthy, SS ;
Beebe, DJ ;
Jiang, HR .
JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, 2005, 14 (06) :1409-1421
[3]  
AGARWALL AK, 2006, P 13 INT C SOL STAT, P364
[4]   Electromagnetic micromotor for microfluidics applications [J].
Barbic, M ;
Mock, JJ ;
Gray, AP ;
Schultz, S .
APPLIED PHYSICS LETTERS, 2001, 79 (09) :1399-1401
[5]   Microfluidic tectonics: A comprehensive construction platform for microfluidic systems [J].
Beebe, DJ ;
Moore, JS ;
Yu, Q ;
Liu, RH ;
Kraft, ML ;
Jo, BH ;
Devadoss, C .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (25) :13488-13493
[6]   Functional hydrogel structures for autonomous flow control inside microfluidic channels [J].
Beebe, DJ ;
Moore, JS ;
Bauer, JM ;
Yu, Q ;
Liu, RH ;
Devadoss, C ;
Jo, BH .
NATURE, 2000, 404 (6778) :588-+
[7]   An electrohydrodynamic polarization micropump for electronic cooling [J].
Darabi, J ;
Ohadi, MM ;
DeVoe, D .
JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, 2001, 10 (01) :98-106
[8]   Adaptive liquid microlenses activated by stimuli-responsive hydrogels [J].
Dong, Liang ;
Agarwal, Abhishek K. ;
Beebe, David J. ;
Jiang, Hongrui .
NATURE, 2006, 442 (7102) :551-554
[9]   EFFECT OF COMONOMER HYDROPHILICITY AND IONIZATION ON THE LOWER CRITICAL SOLUTION TEMPERATURE OF N-ISOPROPYLACRYLAMIDE COPOLYMERS [J].
FEIL, H ;
BAE, YH ;
FEIJEN, J ;
KIM, SW .
MACROMOLECULES, 1993, 26 (10) :2496-2500
[10]   Monolithic integrated microfluidic DNA amplification and capillary electrophoresis analysis system [J].
Lagally, ET ;
Simpson, PC ;
Mathies, RA .
SENSORS AND ACTUATORS B-CHEMICAL, 2000, 63 (03) :138-146