Photothermal Control of the Activity of HRP-Functionalized Gold Nanoparticles

被引:32
作者
Bretschneider, Jan C. [2 ]
Reismann, Maximilian [1 ]
von Plessen, Gero [1 ]
Simon, Ulrich [2 ]
机构
[1] Rhein Westfal TH Aachen, Inst Phys IA, D-52056 Aachen, Germany
[2] Rhein Westfal TH Aachen, Inst Inorgan Chem, D-52074 Aachen, Germany
关键词
biomolecules; gold nanoparticles; horseradish peroxidase; nanostructures; photothermal processes; HORSERADISH-PEROXIDASE; DNA; CYTOTOXICITY; IMMOBILIZATION; NANOZYMES; PROTEINS; ENZYMES;
D O I
10.1002/smll.200900544
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Photothermal control of the enzymatic activity of horseradish peroxidase (HRP) bound to the surface of gold nanoparticles (AuNPs) is demonstrated. Laser light is absorbed by the AuNPs and transformed into heat, which dissipates into the environment of each nanoparticle. This heat influences the enzymatic conversion of ABTS and H2O2 to ABTS+ and H2O, respectively (see image). © 2009 Wiley-VCH Verlag GmbH & Co.
引用
收藏
页码:2549 / 2553
页数:5
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