The vinylogous aldol reaction: A valuable, yet understated carbon-carbon bond-forming maneuver

被引:543
作者
Casiraghi, G
Zanardi, F
Appendino, G
Rassu, G
机构
[1] Univ Parma, Dipartimento Farmaceut, I-43100 Parma, Italy
[2] Univ Turin, Dipartimento Sci & Tecnol Farm, I-10125 Turin, Italy
[3] CNR, Ist Applicaz Tecn Chim Avanzate Problemi Agro, I-07100 Sassari, Italy
关键词
D O I
10.1021/cr990247i
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The vinylogous aldol reactions provides access to a range of structurally diverse targets but has long remained a marginally explored area of organic synthesis. However, its applications have burgeoned in the past few years. Examples are given to demonstrate that vinylogous dienolates and their synthons have a sumptuos aldol chemistry.
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页码:1929 / 1972
页数:44
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