Diffuse large B-cell lymphoma: a heterogeneous group of non-Hodgkin lymphomas comprising several distinct clinicopathological entities

被引：81

作者：

De Paepe, P.

De Wolf-Peeters, C.

机构：

[1] Catholic Univ Louvain, Dept Pathol, Div Morphol & Mol Pathol, B-3000 Louvain, Belgium

[2] AZ St Jan AV, Dept Pathol, B-8000 Brugge, Belgium

来源：

LEUKEMIA | 2007年 / 21卷 / 01期

关键词：

DLBCL; classification; morphology; microarray; immunohistochemistry;

D O I：

10.1038/sj.leu.2404449

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Diffuse large B-cell lymphoma (DLBCL) as defined by the World Health Organization (WHO) classification is clinically, morphologically and genetically a heterogeneous group of malignant proliferations of large lymphoid B cells. Over the last 6 years, several studies have been published improving our understanding of these lymphomas. These studies analyzed DLBCL by their gene expression profile, provided further information on some of the variants of DLBCL listed in the WHO classification and stressed the impact of the site of origin of these tumors. This review summarizes these recent data and explores their impact on the recognition of new clinicopathological lymphoma entities.

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收藏

页码：37 / 43

页数：7

相关论文

共 67 条

[41]

Kaestner KH, 2000, GENE DEV, V14, P142

[42]

Levine Alexandra M, 2006, Semin Oncol Nurs, V22, P80, DOI 10.1016/j.soncn.2006.01.004

[43] Comparison of the expression and prognostic significance of differentiation markers between diffuse large B-cell lymphoma of central nervous system origin and peripheral nodal origin [J].

Lin, CH ;

Ku, KT ;

Chuang, SS ;

Kuo, SH ;

Chang, JH ;

Chang, KC ;

Hsu, HC ;

Tien, HF ;

Cheng, AL .

CLINICAL CANCER RESEARCH, 2006, 12 (04) :1152-1156

[44] Immunohistochemical expression of CD10 and t(14;18) chromosomal translocation may be indicators of follicle centre cell origin in nodal diffuse large B-cell lymphoma [J].

McCluggage, WG ;

Catherwood, M ;

Alexander, HD ;

McBride, HA ;

Smith, MEF ;

Morris, TCM .

HISTOPATHOLOGY, 2002, 41 (05) :414-420

[45] ALK-positive diffuse large B-cell lymphoma of the stomach associated with a clathirin-ALK rearrangement [J].

McManus, DT ;

Catherwood, MA ;

Carey, PD ;

Cuthbert, RJG ;

Alexander, HD .

HUMAN PATHOLOGY, 2004, 35 (10) :1285-1288

[46] BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma [J].

Monni, O ;

Joensuu, H ;

Franssila, K ;

Klefstrom, J ;

Alitalo, K ;

Knuutila, S .

BLOOD, 1997, 90 (03) :1168-1174

[47] Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response [J].

Monti, S ;

Savage, KJ ;

Kutok, JL ;

Feuerhake, F ;

Kurtin, P ;

Mihm, M ;

Wu, BY ;

Pasqualucci, L ;

Neuberg, D ;

Aguiar, RCT ;

Dal Cin, P ;

Ladd, C ;

Pinkus, GS ;

Salles, G ;

Harris, NL ;

Dalla-Favera, R ;

Habermann, TM ;

Aster, JC ;

Golub, TR ;

Shipp, MA .

BLOOD, 2005, 105 (05) :1851-1861

[48] Immunohistochemical profiling based on Bcl-2, CD10 and MUMI expression improves risk stratification in patients with primary nodal diffuse large B cell lymphoma [J].

Muris, JJF ;

Meijer, CJLM ;

Vos, W ;

van Krieken, JHJM ;

Jiwa, NM ;

Ossenkoppele, GJ ;

Oudejans, JJ .

JOURNAL OF PATHOLOGY, 2006, 208 (05) :714-723

[49] Pyothorax-associated lymphoma: A review of 106 cases [J].

Nakatsuka, S ;

Yao, M ;

Hoshida, Y ;

Yamamoto, S ;

Iuchi, K ;

Aozasa, K .

JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (20) :4255-4260

[50] CD10 and Bcl10 expression in diffuse large B-cell lymphoma: CD10 is a marker of improved prognosis [J].

Ohshima, K ;

Kawasaki, C ;

Muta, H ;

Muta, K ;

Deyev, V ;

Haraoka, S ;

Suzumiya, J ;

Podack, ER ;

Kikuchi, M .

HISTOPATHOLOGY, 2001, 39 (02) :156-162

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