Nanoparticle Probes for Structural and Functional Photoacoustic Molecular Tomography

被引:28
作者
Chen, Haobin [1 ,2 ]
Yuan, Zhen [2 ]
Wu, Changfeng [1 ]
机构
[1] Jilin Univ, Coll Elect Sci & Engn, State Key Lab Integrated Optoelect, Changchun 130012, Jilin, Peoples R China
[2] Univ Macau, Fac Hlth Sci, Bioimaging Core, Taipa, Macau, Peoples R China
基金
美国国家科学基金会;
关键词
CONJUGATED POLYMER NANOPARTICLES; IRON-OXIDE NANOPARTICLES; COPPER SULFIDE NANOPARTICLES; UP-CONVERSION NANOPARTICLES; CONTRAST AGENT; PHOTOTHERMAL ABLATION; QUANTUM DOTS; IN-VITRO; MAGNETIC-RESONANCE; CARBON NANOTUBES;
D O I
10.1155/2015/757101
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要
Nowadays, nanoparticle probes have received extensive attention largely due to its potential biomedical applications in structural, functional, and molecular imaging. In addition, photoacoustic tomography (PAT), a method based on the photoacoustic effect, is widely recognized as a robust modality to evaluate the structure and function of biological tissues with high optical contrast and high acoustic resolution. The combination of PAT with nanoparticle probes holds promises for detecting and imaging diseased tissues or monitoring their treatments with high sensitivity. This review will introduce the recent advances in the emerging field of nanoparticle probes and their preclinical applications in PAT, as well as relevant perspectives on future development.
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页数:11
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