Aggregation of DNA-modified nanospheres depending on added polynucleotides

被引:5
作者
Ihara, T [1 ]
Kurohara, K [1 ]
Jyo, A [1 ]
机构
[1] Kumamoto Univ, Fac Engn, Dept Appl Chem & Biochem, Kumamoto 8608555, Japan
关键词
D O I
10.1246/cl.1999.1041
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
DNA oligomer, dT(20), was immobilized onto the organic nanospheres. The spheres aggregated only in the presence of complementary RNA under a special set of conditions. The aggregation was pseudo-reversible for the temperature change. The techniques of the polynucleotide-directed aggregation should be useful for constructing the structure having mesoscopic dimensions.
引用
收藏
页码:1041 / 1042
页数:2
相关论文
共 18 条
[1]  
Blackburn G. M., 1996, NUCL ACIDS CHEM BIOL
[2]  
Cassell AM, 1998, ANGEW CHEM INT EDIT, V37, P1528, DOI 10.1002/(SICI)1521-3773(19980619)37:11<1528::AID-ANIE1528>3.0.CO
[3]  
2-Q
[4]   SYNTHESIS FROM DNA OF A MOLECULE WITH THE CONNECTIVITY OF A CUBE [J].
CHEN, JH ;
SEEMAN, NC .
NATURE, 1991, 350 (6319) :631-633
[5]   Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles [J].
Elghanian, R ;
Storhoff, JJ ;
Mucic, RC ;
Letsinger, RL ;
Mirkin, CA .
SCIENCE, 1997, 277 (5329) :1078-1081
[6]   SEQUENCE-SPECIFIC GENE DETECTION WITH A GOLD ELECTRODE MODIFIED WITH DNA PROBES AND AN ELECTROCHEMICALLY ACTIVE DYE [J].
HASHIMOTO, K ;
ITO, K ;
ISHIMORI, Y .
ANALYTICAL CHEMISTRY, 1994, 66 (21) :3830-3833
[7]   DNA-carrying latex particles for DNA diagnosis. 1. Separation of normal and point mutant DNAs according to the difference in hybridization efficiency [J].
Hatakeyama, M ;
Iwato, S ;
Fujimoto, K ;
Handa, H ;
Kawaguchi, H .
COLLOIDS AND SURFACES B-BIOINTERFACES, 1998, 10 (03) :161-169
[8]   Gene sensor using ferrocenyl oligonucleotide [J].
Ihara, T ;
Nakayama, M ;
Murata, M ;
Nakano, K ;
Maeda, M .
CHEMICAL COMMUNICATIONS, 1997, (17) :1609-1610
[9]   Novel method of detecting mismatch on DNA by using photo-induced electron transfer through DNA [J].
Ihara, T ;
Takata, J ;
Takagi, M .
ANALYTICA CHIMICA ACTA, 1998, 365 (1-3) :49-54
[10]   Modifying the surface features of two-dimensional DNA crystals [J].
Liu, FR ;
Sha, RJ ;
Seeman, NC .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (05) :917-922