Antibiotic susceptibility of bacterial strains isolated from patients with community-acquired urinary tract infections in France

被引:106
作者
Goldstein, FW [1 ]
机构
[1] Hop St Joseph, Microbiol Lab, F-75674 Paris 14, France
关键词
D O I
10.1007/s100960050440
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The aim of this study was to determine the distribution and antibiotic susceptibility patterns of bacterial strains isolated from adults with community-acquired urinary tract infections (UTI) in France. From December 1996 to March 1997, each of 15 private laboratories in France consecutively collected about 80 non-duplicate strains isolated from adult outpatients with UTI, including patients receiving care at home, and tested their susceptibility by the disk diffusion test. A total of 1160 strains were collected: 1031 gram-negative bacilli, including Escherichia coli (n=865), Proteus mirabilis (n = 68) and Klebsiella spp. (n = 40), and 129 grampositive cocci, including Staphylococus aureus (n = 16), other staphylococci (n = 25), group B streptococci (n = 25) and enterococci (n = 63). In the case of 430 bacterial isolates, the patients had either been hospitalised in the last: 6 months or received antibiotic treatment in the last 3 months. The antibiotic susceptibility rates for Escherichia coli were: amoxicillin (58.7%), amoxicillin-clavulanic acid (63.3%), ticarcillin (61.4%), cephalothin (66.8%) cefuroxime (77.6%), cefixime (83.6%), cefotaxime (99.8%), ceftazidime (99%), nalidixic acid (91.9%), norfloxacin (96.6%), ofloxacin (96.3%), ciprofloxacin (98.3%), cotrimoxazole (78.2%), fosfomycin (99.1%) and gentamicin (98.4%). Of the Enterobacteriaceae, five strains produced an extended-spectrum beta-lactamase. Methicillin resistance was detected in nine Staphylococus aureus isolates. The most important findings were two extended-spectrum, beta-lactamase-producing and three methicillin-resistant Staphylococcus aureus strains isolated from patients who had not been hospitalised in the last 6 months or taken antibiotics in the last 3 months. The findings indicate that these strains can spread within the community; therefore, monitoring antibiotic susceptibility of bacteria isolated in the community appears to be mandatory.
引用
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页码:112 / 117
页数:6
相关论文
共 17 条
  • [1] HOSPITAL SURVEILLANCE OF THE SUSCEPTIBILITY OF ESCHERICHIA-COLI AND KLEBSIELLA TO CO-AMOXYCLAV IN 1994
    ALLOUCH, PY
    LABIA, R
    PINA, P
    MORIN, E
    [J]. MEDECINE ET MALADIES INFECTIEUSES, 1995, 25 (8-9): : 934 - 939
  • [2] *COM ANT SOC FRANC, 1998, PATHOL BIOL, V46, pR1
  • [3] Sensitivity to fosfomycin for main urinary tract bacteria infections: A survey on female out-patients, 15 to 65 years of age
    De Mouy, D
    Berges, JL
    Bouilloux, JP
    Charbit, N
    Fischer, I
    Grobost, F
    Larribet, G
    Porcher, T
    [J]. MEDECINE ET MALADIES INFECTIEUSES, 1997, 27 (11): : 903 - 906
  • [4] CHANGING IN ISOLATION RATES AND RESISTANCE PATTERNS OF ESCHERICHIA-COLI ISOLATED FROM COMMUNITY-ACQUIRED URINARY-TRACT INFECTIONS BETWEEN 1986 AND 1993
    DEMOUY, D
    LEPARGNEUR, JP
    AURIOL, JC
    BANDLER, H
    LARRIBET, G
    DECLERCQ, G
    ARMENGAUD, M
    [J]. MEDECINE ET MALADIES INFECTIEUSES, 1994, 24 : 539 - 542
  • [5] DEMOUY D, 1996, BEH, V28, P123
  • [6] RESISTANCE TO CEFTRIAXONE AND OTHER BETA-LACTAMS IN BACTERIA ISOLATED IN THE COMMUNITY
    GOLDSTEIN, FW
    PEAN, Y
    GERTNER, J
    SCAVINER, P
    DESHAYESLARTIGUE, L
    MOUSSION, J
    MOUSSION, J
    CORTEEL, P
    GRELAT, S
    SARZIER, JM
    LEPARGNEUR, JP
    MASSON, P
    PICARD, P
    KUNZELMANN, JM
    MASSOUBRE, B
    NAPOLY, V
    FERMON, I
    LEFEBVRE, E
    MOUNARD, JL
    GOJON, U
    BLANCHON, P
    MASSET, J
    MURAINE, J
    GRIGNON, JC
    VIARDGAUDIN, R
    FORESTIER, G
    GERMAIN, X
    LAUDAT, P
    SCHUH, V
    CHRISTOPHE, AM
    BALMAYER, B
    SESTILANGE, J
    LAHIANI, F
    VALENTIN, JC
    BERT, JY
    DIESNIS, P
    FLORANGE, P
    BROSSET, C
    NAHMANI, A
    QUERCIA, C
    FRANCAIS, JL
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (11) : 2516 - 2519
  • [7] CHARACTERIZATION OF CEFTRIAXONE-RESISTANT ENTEROBACTERIACEAE - A MULTICENTER STUDY IN 26 FRENCH HOSPITALS
    GOLDSTEIN, FW
    PEAN, Y
    ROSATO, A
    GERTNER, J
    GUTMANN, L
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1993, 32 (04) : 595 - 603
  • [8] FREQUENCY OF INHIBITOR-RESISTANT TEM BETA-LACTAMASES IN ESCHERICHIA-COLI ISOLATES FROM URINARY-TRACT INFECTIONS IN FRANCE
    HENQUELL, C
    SIROT, D
    CHANAL, C
    DECHAMPS, C
    CHATRON, P
    LAFEUILLE, B
    TEXIER, P
    SIROT, J
    CLUZEL, R
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1994, 34 (05) : 707 - 714
  • [9] LAYTON MC, 1995, INFECT CONT HOSP EP, V16, P12
  • [10] Escherichia coli: Evolution of resistance to urinary antibiotics including fosfomycin in hospital (11 816 strains, 1991-1995)
    Philippon, A
    Arlet, G
    Lagrange, P
    [J]. MEDECINE ET MALADIES INFECTIEUSES, 1996, 26 (05): : 539 - 541