Imidazole Based Biocompatible Polymer Coating in Deriving <25 nm Functional Nanoparticle Probe for Cellular Imaging and Detection

被引:24
作者
Jana, Nikhil R. [1 ]
Patra, Pranab K. [3 ]
Saha, Arindam [1 ]
Basiruddin, S. K. [1 ]
Pradhan, Narayan [1 ,2 ]
机构
[1] Indian Assoc Cultivat Sci, Ctr Adv Mat, Kolkata 700032, India
[2] Indian Assoc Cultivat Sci, Dept Mat Sci, Kolkata 700032, India
[3] Jubilant Chemsys Ltd, Noida 201301, India
关键词
CDSE/CDS CORE/SHELL NANOCRYSTALS; QUANTUM DOTS; METAL NANOPARTICLES; GOLD NANOPARTICLES; OXIDE NANOCRYSTALS; SCALE SYNTHESIS; IONIC LIQUIDS; SEMICONDUCTOR; SIZE; NANORODS;
D O I
10.1021/jp905685a
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Although synthetic methods for high quality near-monodispersed nanoparticles of metal and semiconductor are well established, their conversion into various functional nanoparticles is challenging. We report here an imidazole based polymer coating that can be used in deriving < 25 nm diameter water-soluble functional nanoparticles. The advantage of this coating method is that it is applicable to various hydrophobic metal and semiconductor nanoparticles, provides different chemical functionality and surface charge to the coated particle, induces minimum cytotoxicity, and can be used in deriving a bifunctional cellular nanoprobe for simultaneous imaging and surface enhanced Raman spectroscopy based detection.
引用
收藏
页码:21484 / 21492
页数:9
相关论文
共 65 条
[1]   Size-dependent dissociation pH of thiolate ligands from cadmium chalcogenide nanocrystals [J].
Aldana, J ;
Lavelle, N ;
Wang, YJ ;
Peng, XG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (08) :2496-2504
[2]   Semiconductor clusters, nanocrystals, and quantum dots [J].
Alivisatos, AP .
SCIENCE, 1996, 271 (5251) :933-937
[3]   From the reactivity of N-heterocyclic carbenes to new chemistry in ionic liquids [J].
Canal, JP ;
Ramnial, T ;
Dickie, DA ;
Clyburne, JAC .
CHEMICAL COMMUNICATIONS, 2006, (17) :1809-1818
[4]   Fluorescent CdSe/ZnS nanocrystal-peptide conjugates for long-term, nontoxic imaging and nuclear targeting in living cells [J].
Chen, FQ ;
Gerion, D .
NANO LETTERS, 2004, 4 (10) :1827-1832
[5]   Intracellular delivery of quantum dots for live cell labeling and organelle tracking [J].
Derfus, AM ;
Chan, WCW ;
Bhatia, SN .
ADVANCED MATERIALS, 2004, 16 (12) :961-+
[6]   In vivo imaging of quantum dots encapsulated in phospholipid micelles [J].
Dubertret, B ;
Skourides, P ;
Norris, DJ ;
Noireaux, V ;
Brivanlou, AH ;
Libchaber, A .
SCIENCE, 2002, 298 (5599) :1759-1762
[7]   A versatile strategy for quantum dot ligand exchange [J].
Dubois, Fabien ;
Mahler, Benoit ;
Dubertret, Benoit ;
Doris, Eric ;
Mioskowski, Charles .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (03) :482-483
[8]   Transition-metal nanoparticles in imidazolium ionic liquids: Recycable catalysts for biphasic hydrogenation reactions [J].
Dupont, J ;
Fonseca, GS ;
Umpierre, AP ;
Fichtner, PFP ;
Teixeira, SR .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (16) :4228-4229
[9]   In vivo cancer targeting and imaging with semiconductor quantum dots [J].
Gao, XH ;
Cui, YY ;
Levenson, RM ;
Chung, LWK ;
Nie, SM .
NATURE BIOTECHNOLOGY, 2004, 22 (08) :969-976
[10]   Luminescent CdSe/CdS core/shell nanocrystals in dendron boxes: Superior chemical, photochemical and thermal stability [J].
Guo, WH ;
Li, JJ ;
Wang, YA ;
Peng, XG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (13) :3901-3909