Catheter-based photoacoustic endoscope

被引：55

作者：

Yang, Joon-Mo ^{[1
]}

Li, Chiye ^{[1
]}

Chen, Ruimin ^{[2
]}

Zhou, Qifa ^{[2
]}

Shung, K. Kirk ^{[2
]}

Wang, Lihong V. ^{[1
]}

机构：

[1] Washington Univ, Dept Biomed Engn, Opt Imaging Lab, St Louis, MO 63130 USA

[2] Univ So Calif, NIH Ultrason Transducer Resource Ctr, Dept Biomed Engn, Los Angeles, CA 90089 USA

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2014年 / 19卷 / 06期

基金：

美国国家卫生研究院;

关键词：

photoacoustic endoscopy; flexible shaft; catheter endoscope; instrument channel; gastrointestinal endoscopy; rabbit esophagus; in vivo imaging; MICROSCOPY; TOMOGRAPHY; ULTRASOUND; BIOPSY;

D O I：

10.1117/1.JBO.19.6.066001

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We report a flexible shaft-based mechanical scanning photoacoustic endoscopy (PAE) system that can be potentially used for imaging the human gastrointestinal tract via the instrument channel of a clinical video endoscope. The development of such a catheter endoscope has been an important challenge to realize the technique's benefits in clinical settings. We successfully implemented a prototype PAE system that has a 3.2-mm diameter and 2.5-m long catheter section. As the instrument's flexible shaft and scanning tip are fully encapsulated in a plastic catheter, it easily fits within the 3.7-mm diameter instrument channel of a clinical video endoscope. Here, we demonstrate the intra-instrument channel workability and in vivo animal imaging capability of the PAE system. (C) 2014 Society of Photo-Optical Instrumentation Engineers (SPIE)

引用

页数：12

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