Organometallic-type reactions in aqueous media mediated by indium. Allylation of acyloyl-imidazoles and pyrazoles. Regioselective synthesis of beta gamma-unsaturated ketones.

被引：32

作者：

Bryan, VJ ^{[1
]}

Chan, TH ^{[1
]}

机构：

[1] MCGILL UNIV,DEPT CHEM,MONTREAL,PQ H3A 2K6,CANADA

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 37期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/S0040-4039(97)01512-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Indium mediated coupling of allylic bromide with acyloyl-imidazoles or pyrazoles in aqueous media gives the corresponding tertiary alcohols or ketones in good yield. The reaction provides a facile regioselective synthesis of beta,gamma-unsaturated ketones and its usefulness is demonstrated by the synthesis of the monoterpene artemesia ketone. (C) 1997 Elsevier Science Ltd.

引用

页码：6493 / 6496

页数：4

共 14 条

[11] ORGANOMETALLIC REACTIONS IN AQUEOUS-MEDIA WITH INDIUM [J].