A role for the ribosome in development

被引:248
作者
Byrne, Mary E. [1 ]
机构
[1] John Innes Inst, Norwich NR4 7UH, Norfolk, England
基金
英国生物技术与生命科学研究理事会;
关键词
DIAMOND-BLACKFAN ANEMIA; AFFECTS PLANT DEVELOPMENT; SEMI-DOMINANT MUTATION; CLASS IIIHD-ZIP; ARABIDOPSIS-THALIANA; DROSOPHILA-MELANOGASTER; TRANSLATIONAL INHIBITION; EMBRYO DEVELOPMENT; AUXIN TRANSPORT; DWARF PHENOTYPE;
D O I
10.1016/j.tplants.2009.06.009
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Development of a multicellular organism involves coordinated cell division, growth and specialization to generate different cell types that contribute to organized tissues, distinct organs and a higher order body plan. This coordinated process requires tight regulation of gene expression, which is mediated by multiple transcriptional, post-transcriptional, translational and post-translational control mechanisms. As I discuss here, recent studies on ribosomal protein genes and ribosome assembly genes indicate that the basic translational machinery of the cell, the ribosome, has a regulatory role in plant development. A comparison between plants and animals reveals both divergent trends in the genome content of ribosomal proteins and intriguing potential overlaps in the role of the ribosome in development.
引用
收藏
页码:512 / 519
页数:8
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