Solid phase synthesis of peptidoglycan monomers for the generation of a combinatorial library

被引：10

作者：

Chan, TY

Chen, A

Allanson, N

Chen, R

Liu, DS

Sofia, MJ

机构：

[1] Transcell Technologies, Inc., Monmouth Junction, NJ 08852

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 45期

关键词：

D O I：

10.1016/0040-4039(96)01849-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Solid phase synthesis of peptidoglycan monomers was conducted by coupling the corresponding lipid-hearing glycocarboxylic acids to resin-bound peptides. The efficiency of coupling reagents was found to be in descending order of HATU>HBTU>PyBOP>EEDQ. There was no obvious difference in coupling yield between conducting the solid phase synthesis on polystyrene resins or on polyethylene glycol grafted polystyrene resins. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：8097 / 8100

页数：4

共 15 条

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