PheP, a putative amino acid permease of Staphylococcus aureus, contributes to survival in vivo and during starvation

被引：15

作者：

Horsburgh, MJ

Wiltshire, MD

Crossley, H

Ingham, E

Foster, SJ

机构：

[1] Univ Sheffield, Dept Mol Biol & Biotechnol, Sheffield S10 2TH, S Yorkshire, England

[2] Univ Leeds, Div Microbiol, Leeds LS2 9JT, W Yorkshire, England

来源：

INFECTION AND IMMUNITY | 2004年 / 72卷 / 05期

关键词：

D O I：

10.1128/IAI.72.5.3073-3076.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

PheP, a putative amino acid permease in Staphylococcus aureus, contributes to starvation survival under glucose-limiting conditions and virulence. A pheP mutation led to poor growth after microaerobic or anaerobic incubation on pig serum agar, which was recovered by phenylalanine addition. Genetic complementation of pheP restored growth and starvation survival.

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页码：3073 / 3076

页数：4

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