IMRT: a review and preview

被引:336
作者
Bortfeld, Thomas
机构
[1] Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA 02114 USA
关键词
D O I
10.1088/0031-9155/51/13/R21
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The very first cornerstone paper on intensity-modulated radiation therapy (IMRT) was published in Physics in Medicine and Biology, and many seminal IMRT works have since appeared in this journal. Today IMRT is a widely used clinical treatment modality in many countries. This contribution to the 50th anniversary issue reviews the physical, mathematical, and technological milestones that have facilitated the clinical implementation and success of IMRT. In particular, the basic concepts and developments of both IMRT treatment planning ('inverse planning') and the delivery of cone-beam IMRT with a multileaf collimator from a fixed number of static beam directions are discussed. An outlook into the future of IMRT concludes the paper.
引用
收藏
页码:R363 / R379
页数:17
相关论文
共 68 条
[1]   Optimization of intensity modulated radiotherapy under constraints for static and dynamic MLC delivery [J].
Alber, M ;
Nüsslin, F .
PHYSICS IN MEDICINE AND BIOLOGY, 2001, 46 (12) :3229-3239
[2]   Modifications to the IMFAST leaf sequencing optimization algorithm [J].
Alfredo, R ;
Siochi, C .
MEDICAL PHYSICS, 2004, 31 (12) :3267-3278
[3]   Radiation therapy: Intensity modulated, image guided, biologically optimized and evidence based [J].
Bentzen, SM .
RADIOTHERAPY AND ONCOLOGY, 2005, 77 (03) :227-230
[4]  
BIRKHOFF GD, 1940, J MATH, V19, P221
[5]   METHODS OF IMAGE-RECONSTRUCTION FROM PROJECTIONS APPLIED TO CONFORMATION RADIOTHERAPY [J].
BORTFELD, T ;
BURKELBACH, J ;
BOESECKE, R ;
SCHLEGEL, W .
PHYSICS IN MEDICINE AND BIOLOGY, 1990, 35 (10) :1423-1434
[6]   REALIZATION AND VERIFICATION OF 3-DIMENSIONAL CONFORMAL RADIOTHERAPY WITH MODULATED FIELDS [J].
BORTFELD, T ;
BOYER, AL ;
SCHLEGEL, W ;
KAHLER, DL ;
WALDRON, TJ .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1994, 30 (04) :899-908
[7]  
BORTFELD T, 1997, 12 INT C US COMP RAD, P1
[8]   X-RAY FIELD COMPENSATION WITH MULTILEAF COLLIMATORS [J].
BORTFELD, TR ;
KAHLER, DL ;
WALDRON, TJ ;
BOYER, AL .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1994, 28 (03) :723-730
[9]   POTENTIAL AND LIMITATIONS OF INVARIANT KERNEL CONFORMAL THERAPY [J].
BOYER, AL ;
DESOBRY, GE ;
WELLS, NH .
MEDICAL PHYSICS, 1991, 18 (04) :703-712
[10]   Intensity-modulated radiotherapy: Current status and issues of interest [J].
Boyer, AL ;
Butler, EB ;
DiPetrillo, TA ;
Engler, MJ ;
Fraass, B ;
Grant, W ;
Ling, CC ;
Low, DA ;
Mackie, TR ;
Mohan, R ;
Purdy, JA ;
Roach, M ;
Rosenman, JG ;
Verhey, LJ ;
Wong, JW ;
Cumberlin, RL ;
Stone, H ;
Palta, JR .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2001, 51 (04) :880-914