学术探索
学术期刊
新闻热点
数据分析
智能评审

IMRT: a review and preview

被引：336
作者：
Bortfeld, Thomas
机构：
[1] Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA 02114 USA
来源：
PHYSICS IN MEDICINE AND BIOLOGY | 2006年 / 51卷 / 13期
关键词：
D O I：
10.1088/0031-9155/51/13/R21
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The very first cornerstone paper on intensity-modulated radiation therapy (IMRT) was published in Physics in Medicine and Biology, and many seminal IMRT works have since appeared in this journal. Today IMRT is a widely used clinical treatment modality in many countries. This contribution to the 50th anniversary issue reviews the physical, mathematical, and technological milestones that have facilitated the clinical implementation and success of IMRT. In particular, the basic concepts and developments of both IMRT treatment planning ('inverse planning') and the delivery of cone-beam IMRT with a multileaf collimator from a fixed number of static beam directions are discussed. An outlook into the future of IMRT concludes the paper.
引用
收藏
页码：R363 / R379
页数：17
相关论文
共 68 条
[21]   THE GENERATION OF INTENSITY-MODULATED FIELDS FOR CONFORMAL RADIOTHERAPY BY DYNAMIC COLLIMATION [J].
CONVERY, DJ ;
ROSENBLOOM, ME .
PHYSICS IN MEDICINE AND BIOLOGY, 1992, 37 (06) :1359-1374
[22]   A PROBLEM IN ROTATION THERAPY WITH X-RAYS [J].
CORMACK, AM .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1987, 13 (04) :623-630
[23]   A PROBLEM IN ROTATION THERAPY WITH X-RAYS - DOSE DISTRIBUTIONS WITH AN AXIS OF SYMMETRY [J].
CORMACK, AM ;
CORMACK, RA .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1987, 13 (12) :1921-1925
[24]   Using voxel-dependent importance factors for interactive DVH-based dose optimization [J].
Cotrutz, C ;
Xing, L .
PHYSICS IN MEDICINE AND BIOLOGY, 2002, 47 (10) :1659-1669
[25]   Leaf position optimization for step-and-shoot IMRT [J].
De Gersem, W ;
Claus, F ;
De Wagter, C ;
Van Duyse, B ;
De Neve, W .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2001, 51 (05) :1371-1388
[26]   COMBINING MULTILEAF FIELDS TO MODULATE FLUENCE DISTRIBUTIONS [J].
GALVIN, JM ;
CHEN, XG ;
SMITH, RM .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1993, 27 (03) :697-705
[27]   CALCULATION OF THE UNCERTAINTY IN THE DOSE DELIVERED DURING RADIATION-THERAPY [J].
GOITEIN, M .
MEDICAL PHYSICS, 1985, 12 (05) :608-612
[28]   A UNIFIED APPROACH TO THE OPTIMIZATION OF BRACHYTHERAPY AND EXTERNAL BEAM DOSIMETRY [J].
HOLMES, T ;
MACKIE, TR ;
SIMPKIN, D ;
RECKWERDT, P .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1991, 20 (04) :859-873
[29]   SHAPING OF ARBITRARY DOSE DISTRIBUTIONS BY DYNAMIC MULTILEAF COLLIMATION [J].
KALLMAN, P ;
LIND, B ;
EKLOF, A ;
BRAHME, A .
PHYSICS IN MEDICINE AND BIOLOGY, 1988, 33 (11) :1291-1300
[30]  
KIJEWSKI P K, 1978, Medical Physics (Woodbury), V5, P426, DOI 10.1118/1.594440
1234567