Nucleic acid molecular switches

被引：124

作者：

Soukup, GA ^{[1
]}

Breaker, RR ^{[1
]}

机构：

[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA

来源：

TRENDS IN BIOTECHNOLOGY | 1999年 / 17卷 / 12期

关键词：

D O I：

10.1016/S0167-7799(99)01383-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Natural and artificial ribozymes can catalyse a diverse range of chemical reactions. Through recent efforts in enzyme engineering, it has become possible to tailor the activity of ribozymes to respond allosterically to specific effector compounds. These allosteric ribozymes function as effector-dependent molecular switches that could find application as novel genetic-control elements, biosensor components or precision switches for use in nanotechnology.

引用

页码：469 / 476

页数：8

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