Shared components of mitochondrial and peroxisomal division

被引:102
作者
Schrader, Michael [1 ]
机构
[1] Univ Marburg, Dept Cell Biol & Cell Pathol, D-35037 Marburg, Germany
来源
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | 2006年 / 1763卷 / 5-6期
关键词
dynamin; fission; Fis1; mitochondria; peroxisome; Pex11;
D O I
10.1016/j.bbamcr.2006.01.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Mitochondria and peroxisomes are ubiquitous subcellular organelles, which are highly dynamic and display large plasticity. Recent studies have led to the surprising finding that both organelles share components of their division machinery, namely the dynamin-related protein DLP1/Drp1 and hFis1, which recruits DLP1/Drp1 to the organelle membranes. This review addresses the current state of knowledge concerning the dynamics and fission of peroxisomes, especially in relation to mitochondrial morphology and division in mammalian cells. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:531 / 541
页数:11
相关论文
共 148 条
[111]   Intermolecular and interdomain interactions of a dynamin-related GTP-binding protein, Dnm1p/Vps1p-like protein [J].
Shin, HW ;
Takatsu, H ;
Mukai, H ;
Munekata, E ;
Murakami, K ;
Nakayama, K .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (05) :2780-2785
[112]   Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells [J].
Smirnova, E ;
Griparic, L ;
Shurland, DL ;
van der Bliek, AM .
MOLECULAR BIOLOGY OF THE CELL, 2001, 12 (08) :2245-2256
[113]   Transcriptome profiling to identify genes involved in peroxisome assembly and function [J].
Smith, JJ ;
Marelli, M ;
Christmas, RH ;
Vizeacoumar, FJ ;
Dilworth, DJ ;
Ideker, T ;
Galitski, T ;
Dimitrov, K ;
Rachubinski, RA ;
Aitchison, JD .
JOURNAL OF CELL BIOLOGY, 2002, 158 (02) :259-271
[114]   Peroxisome synthesis in the absence of preexisting peroxisomes [J].
South, ST ;
Gould, SJ .
JOURNAL OF CELL BIOLOGY, 1999, 144 (02) :255-266
[115]   Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology [J].
Stojanovski, D ;
Koutsopoulos, OS ;
Okamoto, K ;
Ryan, MT .
JOURNAL OF CELL SCIENCE, 2004, 117 (07) :1201-1210
[116]  
STOJANOVSKI D, 2005, FEBS IUBMG WORKSH MI
[117]   Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring [J].
Stowell, MHB ;
Marks, B ;
Wigge, P ;
McMahon, HT .
NATURE CELL BIOLOGY, 1999, 1 (01) :27-32
[118]   Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission [J].
Suzuki, M ;
Neutzner, A ;
Tjandra, N ;
Youle, RJ .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (22) :21444-21452
[119]   The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle [J].
Suzuki, M ;
Jeong, SY ;
Karbowski, M ;
Youle, RJ ;
Tjandra, N .
JOURNAL OF MOLECULAR BIOLOGY, 2003, 334 (03) :445-458
[120]   Dynamin undergoes a GTP-dependent conformational change causing vesiculation [J].
Sweitzer, SM ;
Hinshaw, JE .
CELL, 1998, 93 (06) :1021-1029