Cancer therapeutics in yeast

被引：31

作者：

Bjornsti, MA ^{[1
]}

机构：

[1] St Jude Childrens Res Hosp, Dept Mol Pharmacol, Memphis, TN 38105 USA

来源：

CANCER CELL | 2002年 / 2卷 / 04期

关键词：

D O I：

10.1016/S1535-6108(02)00160-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The budding yeast Saccharomyces cerevisiae is a genetically tractable model system with which to establish the cellular target of a given agent and investigate mechanisms of drug action. Copyright © 2002 Cell Press.

引用

页码：267 / 273

页数：7

共 45 条

[21] Gene disruption [J].

Johnston, M ;

Riles, L ;

Hegemann, JH .

GUIDE TO YEAST GENETICS AND MOLECULAR AND CELL BIOLOGY, PT B, 2002, 350 :290-315

[22] Cascades of mammalian caspase activation in the yeast Saccharomyces cerevisiae [J].

Kang, JJ ;

Schaber, MD ;

Srinivasula, SM ;

Alnemri, ES ;

Litwack, G ;

Hall, DJ ;

Bjornsti, MA .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (05) :3189-3198

[23] SCT1 MUTANTS SUPPRESS THE CAMPTOTHECIN SENSITIVITY OF YEAST-CELLS EXPRESSING WILD-TYPE DNA TOPOISOMERASE-I [J].

KAUH, EA ;

BJORNSTI, MA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (14) :6299-6303

[24] Regulation of pleiotropic drug resistance in yeast [J].

Kolaczkowska, A ;

Goffeau, A .

DRUG RESISTANCE UPDATES, 1999, 2 (06) :403-414

[25] Emerging technologies in yeast genomics [J].

Kumar, A ;

Snyder, M .

NATURE REVIEWS GENETICS, 2001, 2 (04) :302-312

[26] Classical mutagenesis techniques [J].

Lawrence, CW .

GUIDE TO YEAST GENETICS AND MOLECULAR AND CELL BIOLOGY, PT B, 2002, 350 :189-199

[27] New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system [J].

Le Crom, S ;

Devaux, F ;

Marc, P ;

Zhang, XT ;

Moye-Rowley, WS ;

Jacq, C .

MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (08) :2642-2649

[28] Monitoring S phase progression globally and locally using BrdU incorporation in TK+ yeast strains [J].

Lengronne, A ;

Pasero, P ;

Bensimon, A ;

Schwob, E .

NUCLEIC ACIDS RESEARCH, 2001, 29 (07) :1433-1442

[29] Constructing yeast libraries [J].

Liu, HP .

GUIDE TO YEAST GENETICS AND MOLECULAR AND CELL BIOLOGY, PT B, 2002, 350 :72-86

[30]

Longtine MS, 1998, YEAST, V14, P953, DOI 10.1002/(SICI)1097-0061(199807)14:10<953::AID-YEA293>3.3.CO

← 1 2 3 4 5 →