Generating rats with conditional alleles using CRISPR/Cas9

被引：157

作者：

Ma, Yuanwu ^{[1
]}

Zhang, Xu ^{[1
]}

Shen, Bin ^{[2
]}

Lu, Yingdong ^{[1
]}

Chen, Wei ^{[1
]}

Ma, Jing ^{[1
]}

Bai, Lin ^{[1
]}

Huang, Xingxu ^{[2
]}

Zhang, Lianfeng ^{[1
]}

机构：

[1] Chinese Acad Med Sci, Inst Lab Anim Sci, Minist Hlth, Key Lab Human Dis Comparat Med, Beijing 100021, Peoples R China

[2] Nanjing Univ, Nanjing Biomed Res Inst, Natl Resource Ctr Mutant Mice, Model Anim Res Ctr,MOE Key Lab Model Anim Dis Stu, Nanjing 210061, Jiangsu, Peoples R China

来源：

CELL RESEARCH | 2014年 / 24卷 / 01期

关键词：

SYSTEM; KNOCKOUT; MICE;

D O I：

10.1038/cr.2013.157

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：122 / 125

页数：4

共 10 条

[1] In vivo genome editing using a high-efficiency TALEN system [J].

Bedell, Victoria M. ;

Wang, Ying ;

Campbell, Jarryd M. ;

Poshusta, Tanya L. ;

Starker, Colby G. ;

Krug, Randall G., II ;

Tan, Wenfang ;

Penheiter, Sumedha G. ;

Ma, Alvin C. ;

Leung, Anskar Y. H. ;

Fahrenkrug, Scott C. ;

Carlson, Daniel F. ;

Voytas, Daniel F. ;

Clark, Karl J. ;

Essner, Jeffrey J. ;

Ekker, Stephen C. .

NATURE, 2012, 491 (7422) :114-U133

[2] Whole-rat conditional gene knockout via genome editing [J].

Brown, Andrew J. ;

Fisher, Daniel A. ;

Kouranova, Evguenia ;

McCoy, Aaron ;

Forbes, Kevin ;

Wu, Yumei ;

Henry, Rachel ;

Ji, Diana ;

Chambers, Andre ;

Warren, Joe ;

Shu, Weiguo ;

Weinstein, Edward J. ;

Cui, Xiaoxia .

NATURE METHODS, 2013, 10 (07) :638-+

[3] Targeted integration in rat and mouse embryos with zinc- finger nucleases [J].

Cui, Xiaoxia ;

Ji, Diana ;

Fisher, Daniel A. ;

Wu, Yumei ;

Briner, David M. ;

Weinstein, Edward J. .

NATURE BIOTECHNOLOGY, 2011, 29 (01) :64-+

[4] Establishing, maintaining and modifying DNA methylation patterns in plants and animals [J].

Law, Julie A. ;

Jacobsen, Steven E. .

NATURE REVIEWS GENETICS, 2010, 11 (03) :204-220

[5] Heritable gene targeting in the mouse and rat using a CRISPR-Cas system [J].

Li, Dali ;

Qiu, Zhongwei ;

Shao, Yanjiao ;

Chen, Yuting ;

Guan, Yuting ;

Liu, Meizhen ;

Li, Yongmei ;

Gao, Na ;

Wang, Liren ;

Lu, Xiaoling ;

Zhao, Yongxiang ;

Liu, Mingyao .

NATURE BIOTECHNOLOGY, 2013, 31 (08) :681-683

[6] Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems [J].

Li, Wei ;

Teng, Fei ;

Li, Tianda ;

Zhou, Qi .

NATURE BIOTECHNOLOGY, 2013, 31 (08) :684-686

[7] The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli [J].

Sapranauskas, Rimantas ;

Gasiunas, Giedrius ;

Fremaux, Christophe ;

Barrangou, Rodolphe ;

Horvath, Philippe ;

Siksnys, Virginijus .

NUCLEIC ACIDS RESEARCH, 2011, 39 (21) :9275-9282

[8] Generation of gene-modified mice via Cas9/RNA-mediated gene targeting [J].

Shen, Bin ;

Zhang, Jun ;

Wu, Hongya ;

Wang, Jianying ;

Ma, Ke ;

Li, Zheng ;

Zhang, Xueguang ;

Zhang, Pumin ;

Huang, Xingxu .

CELL RESEARCH, 2013, 23 (05) :720-723

[9] Knockout rats generated by embryo microinjection of TALENs [J].

Tesson, Laurent ;

Usal, Claire ;

Menoret, Severine ;

Leung, Elo ;

Niles, Brett J. ;

Remy, Severine ;

Santiago, Yolanda ;

Vincent, Anna I. ;

Meng, Xiangdong ;

Zhang, Lei ;

Gregory, Philip D. ;

Anegon, Ignacio ;

Cost, Gregory J. .

NATURE BIOTECHNOLOGY, 2011, 29 (08) :695-696

[10] One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering [J].

Yang, Hui ;

Wang, Haoyi ;

Shivalila, Chikdu S. ;

Cheng, Albert W. ;

Shi, Linyu ;

Jaenisch, Rudolf .

CELL, 2013, 154 (06) :1370-1379

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