Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2008

被引:67
作者
Dolle, Roland E. [1 ]
Le Bourdonnec, Bertrand [1 ]
Goodman, Allan J. [1 ]
Morales, Guillermo A. [2 ]
Thomas, Craig J. [3 ]
Zhang, Wei [4 ]
机构
[1] Adolor Corp, Exton, PA 19341 USA
[2] Semafore Pharmaceut Inc, Indianapolis, IN 46268 USA
[3] NHGRI, NIH, Chem Genom Ctr, Rockville, MD 20850 USA
[4] Univ Massachusetts, Dept Chem, Boston, MA 02125 USA
来源
JOURNAL OF COMBINATORIAL CHEMISTRY | 2009年 / 11卷 / 05期
关键词
ONE-POT SYNTHESIS; SOLID-PHASE SYNTHESIS; MICROWAVE-ASSISTED SYNTHESIS; DIVERSITY-ORIENTED SYNTHESIS; DIELS-ALDER REACTIONS; CATALYZED ONE-POT; SMALL-MOLECULE INHIBITOR; PARALLEL SOLUTION-PHASE; 1,3,4,4-TETRASUBSTITUTED BETA-LACTAMS; REVERSE-TRANSCRIPTASE INHIBITORS;
D O I
10.1021/cc9000828
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
[No abstract available]
引用
收藏
页码:739 / 790
页数:52
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    Aufort, Marie
    Herscovici, Jean
    Bouhours, Pascale
    Moreau, Nicole
    Girard, Christian
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (03) : 1195 - 1198
  • [32] Robotic hierarchical mixing for the production of combinatorial libraries of proteins and small molecules
    Avramova, Larisa V.
    Desai, Jairav
    Weaver, Shelley
    Friedman, Alan M.
    Bailey-Kellogg, Chris
    [J]. JOURNAL OF COMBINATORIAL CHEMISTRY, 2008, 10 (01): : 63 - 68
  • [33] A one-pot, solid-phase synthesis of secondary amines from reactive alkyl halides and an alkyl azide
    Ayesa, Susana
    Samuelsson, Bertil
    Classon, Bjorn
    [J]. SYNLETT, 2008, (01) : 97 - 99
  • [34] Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38MAPK inhibitor RO3201195 for study in Werner syndrome cells
    Bagley, Mark C.
    Davis, Terence
    Dix, Matthew C.
    Murziani, Paola G. S.
    Rokicki, Michal J.
    Kipling, David
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (13) : 3745 - 3748
  • [35] A novel, microwave-assisted method for the synthesis of alicyclic-condensed 5H-1,4,6,7-tetrahydro-1,4-diazepin-5-ones
    Balazs, Arpad
    Van der Eycken, Erik
    Fulop, Ferenc
    [J]. TETRAHEDRON LETTERS, 2008, 49 (28) : 4333 - 4335
  • [36] Kinase array design, back to front: Biaryl amides
    Baldwin, Ian
    Bamborough, Paul
    Haslam, Claudine G.
    Hunjan, Suchete S.
    Longstaff, Tim
    Mooney, Christopher J.
    Patel, Shila
    Quinn, Jo
    Somers, Don O.
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (19) : 5285 - 5289
  • [37] Assessment of Chemical Coverage of Kinome Space and Its Implications for Kinase Drug Discovery
    Bamborough, Paul
    Drewry, David
    Harper, Gavin
    Smith, Gary K.
    Schneider, Klaus
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (24) : 7898 - 7914
  • [38] Multicomponent synthesis of benzoxazinones via tandem Ugi/Mitsunobu reactions: an unexpected cine-substitution
    Banfi, Luca
    Basso, Andrea
    Guanti, Giuseppe
    Lecinska, Paulina
    Riva, Renata
    [J]. MOLECULAR DIVERSITY, 2008, 12 (3-4) : 187 - 190
  • [39] Polyfunctionalized pyrrolidines by Ugi multicomponent reaction followed by palladium-mediated SN2′ cyclizations
    Banfi, Luca
    Basso, Andrea
    Cerulli, Valentina
    Guanti, Giuseppe
    Riva, Renata
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2008, 73 (04) : 1608 - 1611
  • [40] A small molecular scaffold for selective inhibition of Wip1 phosphatase
    Bang, Jeong
    Yamaguchi, Hiroshi
    Durell, Stewart R.
    Appella, Ettore
    Appella, Daniel H.
    [J]. CHEMMEDCHEM, 2008, 3 (02) : 230 - 232