SNAREs - engines for membrane fusion

被引：1983

作者：

Jahn, Reinhard

Scheller, Richard H.

机构：

[1] Max Planck Inst Biophys Chem, Dept Neurobiol, D-37077 Gottingen, Germany

[2] Genentech Inc, San Francisco, CA 94080 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2006年 / 7卷 / 09期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrm2002

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Since the discovery of SNARE proteins in the late 1980s, SNAREs have been recognized as key components of protein complexes that drive membrane fusion. Despite considerable sequence divergence among SNARE proteins, their mechanism seems to be conserved and is adaptable for fusion reactions as diverse as those involved in cell growth, membrane repair, cytokinesis and synaptic transmission. A fascinating picture of these robust nanomachines is emerging.

引用

收藏

页码：631 / 643

页数：13

相关论文

共 152 条

[101] Topological restriction of SNARE-dependent membrane fusion [J].

Parlati, F ;

McNew, JA ;

Fukuda, R ;

Miller, R ;

Söllner, TH ;

Rothman, JE .

NATURE, 2000, 407 (6801) :194-198

[102] The specificity of SNARE-dependent fusion is encoded in the SNARE motif [J].

Paumet, F ;

Rahimian, V ;

Rothman, JE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (10) :3376-3380

[103] The di-leucine motif of vesicle-associated membrane protein 4 is required for its localization and AP-1 binding [J].

Peden, AA ;

Park, GY ;

Scheller, RH .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (52) :49183-49187

[104] SNAREs involved in traffic through the Golgi complex [J].

Pelham, HRB ;

Banfield, DK ;

Lewis, MJ .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1995, 60 :105-111

[105] Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes [J].

Peng, RW ;

Gallwitz, D .

JOURNAL OF CELL BIOLOGY, 2002, 157 (04) :645-655

[106] Synaptophysin I controls the targeting of VAMP2/synaptobrevin II to synaptic vesicles [J].

Pennuto, M ;

Bonanomi, D ;

Benfenati, F ;

Valtorta, F .

MOLECULAR BIOLOGY OF THE CELL, 2003, 14 (12) :4909-4919

[107] Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion [J].

Peters, C ;

Bayer, MJ ;

Bühler, S ;

Andersen, JS ;

Mann, M ;

Mayer, A .

NATURE, 2001, 409 (6820) :581-588

[108] Targeting RAB GTPases to distinct membrane compartments [J].

Pfeffer, S ;

Aivazian, D .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2004, 5 (11) :886-896

[109] Structural basis for the inhibitory role of tomosyn in exocytosis [J].

Pobbati, AV ;

Razeto, A ;

Böddener, M ;

Becker, S ;

Fasshauer, D .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (45) :47192-47200

[110] Cholesterol-dependent syntaxin-4 and SNAP-23 clustering regulates caveolar fusion with the endothelial plasma membrane [J].

Predescu, SA ;

Predescu, DN ;

Shimizu, K ;

Klein, IK ;

Malik, AB .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (44) :37130-37138

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