Stereoselective synthesis of microcarpalide

被引：80

作者：

Murga, J

Falomir, E

García-Fortanet, J

Carda, M ^{[1
]}

Marco, JA

机构：

[1] Univ Jaume 1, UP Quim Inorgan & Organ, E-12080 Castellon de La Plana, Spain

[2] Univ Valencia, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 20期

关键词：

D O I：

10.1021/ol0265463

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The first total synthesis of the naturally occurring nonenolide, microcarpailde, is described. The key step in the synthesis was the ring-closing metathesis of a dienic ester prepared in turn by coupling an acid and an alcohol stereoselectively synthesized from (S,S)-tartaric acid and (R)-glycidol, respectively.

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页码：3447 / 3449

页数：3

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