Preparation of 124I solutions after thermodistillation of irradiated 124TeO2 targets

被引:48
作者
Knust, EJ
Dutschka, K
Weinreich, R [1 ]
机构
[1] Univ Hosp Essen, Dept Nucl Med, D-45122 Essen, Germany
[2] Paul Scherrer Inst, Lab Radio & Environm Chem, CH-5232 Villigen, Switzerland
关键词
radionuclide production; I-124; thermodistillation;
D O I
10.1016/S0969-8043(99)00127-X
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The 4.15-d radionuclide I-124 is produced via the nuclear reaction Te-124(d, 2n) I-124 by irradiation of 96% enriched (TeO2)-Te-124 with 14 MeV deuterons, followed by thermodistillation. In order to minimise the loss of I-124, the quartz distillation tube was fitted to a stainless steel helix capillary trap directly behind the end of the furnace. Using this device, distillation yields of more than 80% were routinely obtained, and the activity was concentrated in markedly less than 100 mu L solution. The I-124 produced by this method proved to be useful for labelling proteins and IUdR. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:181 / 184
页数:4
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