Fitness cost of SCCmec and methicillin resistance levels in staphylococcus aureus

被引：125

作者：

Ender, M ^{[1
]}

McCallum, N ^{[1
]}

Adhikari, R ^{[1
]}

Berger-Bächi, B ^{[1
]}

机构：

[1] Univ Zurich, Dept Med Microbiol, CH-8028 Zurich, Switzerland

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 06期

关键词：

D O I：

10.1128/AAC.48.6.2295-2297.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Transformation of a type I SCCmec element into Staphylococcus aureus yielded highly oxacillin-resistant transformants with a reduced growth rate. Faster-growing variants could again be selected at the cost of reduced resistance levels, demonstrating an inverse correlation between oxacillin resistance levels and growth rate.

引用

页码：2295 / 2297

页数：3

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