Trimethylamine biosensor based on pentacene enzymatic organic field effect transistor

被引：28

作者：

Diallo, A. K. ^{[1
]}

Tardy, J. ^{[1
]}

Zhang, Z. Q. ^{[2
]}

Bessueille, F. ^{[2
]}

Jaffrezic-Renault, N. ^{[2
]}

Lemiti, M. ^{[3
]}

机构：

[1] Ecole Cent Lyon, Lyon Inst Nanotechnol, CNRS, UMR 5270, F-69134 Ecully, France

[2] Univ Lyon 1, Sci Analyt Lab, CNRS, UMR 5180, F-69622 Villeurbanne, France

[3] Inst Natl Sci Appl, Lyon Inst Nanotechnol, CNRS, UMR 5270, F-69621 Villeurbanne, France

来源：

APPLIED PHYSICS LETTERS | 2009年 / 94卷 / 26期

关键词：

biosensors; organic compounds; organic field effect transistors; THIN-FILM TRANSISTORS; FISH-FRESHNESS; SENSING PROPERTIES; SENSORS; PH;

D O I：

10.1063/1.3167805

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

This paper reports on an enzymatic organic field effect transistor based biosensor dedicated to the detection of trimethylamine, in view of fish freshness assessment. Flexible devices were processed on Kapton substrate with pentacene as organic semiconductor and Parylene-C as top gate dielectric. Proton sensitive dielectric surface was achieved by depositing a thin hydrogenated silicon nitride layer at moderate temperature on Parylene. An enzymatic membrane made of flavin-containing mono-oxygenase 3 cross-linked with bovine serum albumin deposited on silicon nitride completed the realization of the device. High sensitivity trimethylamine biosensing was demonstrated in the 0-8 ppm range.

引用

页数：3

共 24 条

[1] Organic thin-film transistors as transducers for (bio) analytical applications
Bartic, C
Borghs, G
[J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2006, 384 (02) : 354 - 365
[2] Field-effect detection of chemical species with hybrid organic/inorganic transistors
Bartic, C
Campitelli, A
Borghs, S
[J]. APPLIED PHYSICS LETTERS, 2003, 82 (03) : 475 - 477
[3] Monitoring pH with organic-based field-effect transistors
Bartic, C
Palan, B
Campitelli, A
Borghs, G
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 2002, 83 (1-3) : 115 - 122
[4] Thirty years of ISFETOLOGY - What happened in the past 30 years and what may happen in the next 30 years
Bergveld, P
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 2003, 88 (01) : 1 - 20
[5] Array of lutetium bisphthalocyanine sensors for the detection of trimethylamine
de Saja, R
Souto, J
Rodríguez-Méndez, ML
de Saja, JA
[J]. MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 1999, 8-9 : 565 - 568
[6] Growth related properties of pentacene thin film transistors with different gate dielectrics
Deman, A. -L.
Erouel, M.
Lallemand, D.
Phaner-Goutorbe, M.
Lang, P.
Tardy, J.
[J]. JOURNAL OF NON-CRYSTALLINE SOLIDS, 2008, 354 (15-16) : 1598 - 1607
[7] Flexible pentacene ion sensitive field effect transistor with a hydrogenated silicon nitride surface treated Parylene top gate insulator
Diallo, K.
Lemiti, M.
Tardy, J.
Bessueille, F.
Jaffrezic-Renault, N.
[J]. APPLIED PHYSICS LETTERS, 2008, 93 (18)
[8] Stability of pentacene top gated thin film transistors
Diallo, K.
Erouel, M.
Tardy, J.
Andre, E.
Garden, J.-L.
[J]. APPLIED PHYSICS LETTERS, 2007, 91 (18)
[9] Development of a microconductometric biosniffer for detection of trimethylamine
Fillit, Chrystelle
Jaffrezic-Renault, Nicole
Bessueille, Francois
Leonard, Didier
Mitsubayashi, Kohji
Tardy, Jacques
[J]. MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2008, 28 (5-6): : 781 - 786
[10] Gao C, 2003, BOSTON TRANSDUCERS'03: DIGEST OF TECHNICAL PAPERS, VOLS 1 AND 2, P1172

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