2-Thioindoles as precursors to spiro-fused indolines:: Synthesis of (±)-dehaloperophoramidine

被引：61

作者：

Sabahi, Amir ^{[1
]}

Novikov, Alexei ^{[1
]}

Rainier, Jon D. ^{[1
]}

机构：

[1] Univ Utah, Dept Chem, Salt Lake City, UT 84112 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 26期

关键词：

communesin; cyclization; natural products; perophoramidine; thioindoles;

D O I：

10.1002/anie.200601278

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Closing the ring: The cyclization of a 2-thioindole with an electrophilic substituent serves as the key transformation in a synthetic strategy for the generation of indole alkaloids of the perophoramidine and communesin class. DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene, Ms = methanesulfonyl chloride. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：4317 / 4320

页数：4

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