Craniofacial bone reconstruction with bioactive fiber-reinforced composite implant

被引:62
作者
Aitasalo, Kalle M. J. [1 ]
Piitulainen, Jaakko M. [1 ,2 ]
Rekola, Jami [1 ]
Vallittu, Pekka K. [2 ]
机构
[1] Turku Univ Hosp, Dept Otorhinolaryngol Head & Neck Surg, Turku 20521, Finland
[2] Univ Turku, Inst Dent, Turku Clin Biomat Ctr TCBC, Turku, Finland
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2014年 / 36卷 / 05期
关键词
craniofacial bone reconstruction; craniotomy; fiber-reinforced composite; bioactive glass; skull bone defect; IN-VITRO CYTOTOXICITY; FLEXURAL PROPERTIES; DECOMPRESSIVE CRANIECTOMY; GLASS S53P4; COMPUTED-TOMOGRAPHY; RESIDUAL MONOMERS; TITANIUM; SKULL; RESIN; CRANIOPLASTY;
D O I
10.1002/hed.23370
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 [耳鼻咽喉科学];
摘要
Background A novel, bioactive, fiber-reinforced composite implant is a solution to address the shortcomings in craniofacial bone reconstruction. A longitudinal clinical investigation with a follow-up time of 4 years was conducted. Methods A cranial bone reconstruction with the implant was performed on 12 patients. In these patients, the reasons for craniotomies resulting in craniofacial bone defects were traumatic and spontaneous intracranial bleeding as well as infections to the primary reconstruction material. The implant material consisted of a supporting fiber-reinforced framework, porous inner layers, and a bioactive glass (BG; S53P4) filling. The framework and the porous layers were made of a bisphenol-a-glycidyl methacrylate and triethyleneglycoldi-methacrylate (pBisGMA-pTEGDMA) resin matrix, which was reinforced with silanized E-glass. Results In clinical examinations and skull X-rays, the implants were in original positions providing the expected functional and aesthetic outcome at all time points. Conclusion The implants functioned appropriately, which would provide a potential solution for craniofacial bone reconstruction in the future. (c) 2013 Wiley Periodicals, Inc. Head Neck 36: 722-728, 2014
引用
收藏
页码:722 / 728
页数:7
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