What is an adult stem cell?

被引：114

作者：

Clevers, Hans ^{[1
,2
]}

机构：

[1] Hubrecht Inst, Dept Dev Biol & Stem Cell Res, Utrecht, Netherlands

[2] Univ Med Ctr, Utrecht, Netherlands

来源：

SCIENCE | 2015年 / 350卷 / 6266期

关键词：

MAMMARY-GLAND; HOMEOSTASIS; EPITHELIUM; REPAIR; CRYPT;

D O I：

10.1126/science.aad7016

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];

摘要：

[No abstract available]

引用

收藏

页码：1319 / 1320

页数：2

相关论文

共 18 条

[1]

Tissue-Specific Stem Cells: Lessons from the Skeletal Muscle Satellite Cell [J].

Brack, Andrew S. ;

Rando, Thomas A. .

CELL STEM CELL, 2012, 10 (05) :504-514

[2]

Intestinal label-retaining cells are secretory precursors expressing Lgr5 [J].

Buczacki, Simon J. A. ;

Zecchini, Heather Ireland ;

Nicholson, Anna M. ;

Russell, Roslin ;

Vermeulen, Louis ;

Kemp, Richard ;

Winton, Douglas J. .

NATURE, 2013, 495 (7439) :65-69

[3]

A single type of progenitor cell maintains normal epidermis [J].

Clayton, Elizabeth ;

Doupe, David P. ;

Klein, Allon M. ;

Winton, Douglas J. ;

Simons, Benjamin D. ;

Jones, Philip H. .

NATURE, 2007, 446 (7132) :185-189

[4]

The Intestinal Crypt, A Prototype Stem Cell Compartment [J].

Clevers, Hans .

CELL, 2013, 154 (02) :274-284

[5]

A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium [J].

Doupe, David P. ;

Alcolea, Maria P. ;

Roshan, Amit ;

Zhang, Gen ;

Klein, Allon M. ;

Simons, Benjamin D. ;

Jones, Philip H. .

SCIENCE, 2012, 337 (6098) :1091-1093

[6]

The hair follicle-a stem cell zoo [J].

Jaks, Viljar ;

Kasper, Maria ;

Toftgard, Rune .

EXPERIMENTAL CELL RESEARCH, 2010, 316 (08) :1422-1428

[7]

Mouse Germ Line Stem Cells Undergo Rapid and Stochastic Turnover [J].

Klein, Allon M. ;

Nakagawa, Toshinori ;

Ichikawa, Rie ;

Yoshida, Shosei ;

Simons, Benjamin D. .

CELL STEM CELL, 2010, 7 (02) :214-224

[8]

Lgr5+ Gastric Stem Cells Divide Symmetrically to Effect Epithelial Homeostasis in the Pylorus [J].

Leushacke, Marc ;

Ng, Annie ;

Galle, Joerg ;

Loeffler, Markus ;

Barker, Nick .

CELL REPORTS, 2013, 5 (02) :349-356

[9]

In situ identification of bipotent stem cells in the mammary gland [J].

Rios, Anne C. ;

Fu, Nai Yang ;

Lindeman, Geoffrey J. ;

Visvader, Jane E. .

NATURE, 2014, 506 (7488) :322-+

[10]

Generation of a functional mammary gland from a single stem cell [J].

Shackleton, M ;

Vaillant, F ;

Simpson, KJ ;

Stingl, J ;

Smyth, GK ;

Asselin-Labat, ML ;

Wu, L ;

Lindeman, GJ ;

Visvader, JE .

NATURE, 2006, 439 (7072) :84-88