From analog to digital: exploring cell dynamics with single quantum dots

被引:19
作者
Dahan, M [1 ]
机构
[1] Ecole Normale Super, Lab Kastler Brossel, F-75005 Paris, France
关键词
quantum dots; live cells; biological imaging; single molecule tracking;
D O I
10.1007/s00418-005-0105-x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Semiconductor quantum dots (QDs) have emerged as new fluorescent probes for biology. When combined with ultrasensitive optical techniques, they allow motions of individual biomolecules to be tracked in live cells with high signal-to-noise and over unprecedented durations. Single QD imaging readily offers a powerful tool to investigate the organization in cell membranes. Altogether QDs will contribute to more advanced biological imaging and enable new studies on the dynamics of cellular processes.
引用
收藏
页码:451 / 456
页数:6
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