Improved enantioselectivity in the epoxidation of cinnamic acid derivatives with dioxiranes from keto bile acids

被引：30

作者：

Bortolini, O

Fantin, G

Fogagnolo, M

Forlani, R

Maietti, S

Pedrini, P

机构：

[1] Univ Ferrara, Dipartimento Chim, I-44100 Ferrara, Italy

[2] Dipartimento Risorse Nat & Culturali, I-44100 Ferrara, Italy

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 16期

关键词：

D O I：

10.1021/jo020146b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The asymmetric epoxidation of substituted cinnamic acids has been obtained in the presence of different keto bile acid derivatives as optically active carbonyl inducers and Oxone as oxygen source. Predominant or almost exclusive formation of both enantiomeric epoxides is obtained (ee up to 95%) depending on the specific substitution at carbons C(7) and C(12) of the bile acid.

引用

页码：5802 / 5806

页数：5

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