Multicomponent one-pot diastereoselective synthesis of biologically important scaffold under microwaves

被引：33

作者：

Dandia Anshu ^{[1
]}

Singh Ruby ^{[1
]}

Sarawgi Pritima ^{[1
]}

Khaturia Sarita ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

CHINESE JOURNAL OF CHEMISTRY | 2006年 / 24卷 / 07期

关键词：

multi-component reaction; microwave; spiro derivative;

D O I：

10.1002/cjoc.200690180

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and fast three-component diastereoselective synthesis of biologically important spiro scaffold 4 was carried out in reasonable purity starting from readily available 1H-indole-2,3-dione 1, ethyl cyanoacetate 2 and 4-hydroxycoumarin 3 under microwave in high yield (88%-92%) and short time.

引用

页码：950 / 954

页数：5

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