Platinum-catalyzed intramolecular asymmetric hydroarylation of unactivated alkenes with indoles

被引：128

作者：

Han, Xiaoqing ^{[1
]}

Widenhoefer, Ross A. ^{[1
]}

机构：

[1] Duke Univ, PM Gross Chem Lab, Durham, NC 27708 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 17期

关键词：

D O I：

10.1021/ol061441b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A 1: 1 mixture of the platinum bis(phosphine) complex [(S)-4]PtCl2[(S)-4 = (S)-3,5-t-Bu-4-MeO-MeOBIPHEP] catalyzes the intramolecular asymmetric hydroarylation of 2-(4-pentenyl) indoles in moderate to good yield with up to 90% ee.

引用

页码：3801 / 3804

页数：4

共 44 条

[1] Synthesis of a tricyclic mescaline analogue by catalytic C-H bond activation
Ahrendt, KA
Bergman, RG
Ellman, JA
[J]. ORGANIC LETTERS, 2003, 5 (08) : 1301 - 1303
[2] Platinum-catalyzed intramolecular hydroamination of unactivated olefins with secondary alkylamines
Bender, CF
Widenhoefer, RA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (04) : 1070 - 1071
[3] SYNTHESIS OF CARBAZOLE ALKALOIDS
BERGMAN, J
PELCMAN, B
[J]. PURE AND APPLIED CHEMISTRY, 1990, 62 (10) : 1967 - 1976
[4] Blaser HU, 1999, SYNLETT, P867
[5] THE PICTET-SPENGLER CONDENSATION - A NEW DIRECTION FOR AN OLD REACTION
COX, ED
COOK, JM
[J]. CHEMICAL REVIEWS, 1995, 95 (06) : 1797 - 1842
[6] Palladium/BINAP(S)-catalyzed asymmetric allylic amination
Faller, JW
Wilt, JC
[J]. ORGANIC LETTERS, 2005, 7 (04) : 633 - 636
[7] Girard C, 1998, ANGEW CHEM INT EDIT, V37, P2923, DOI 10.1002/(SICI)1521-3773(19981116)37:21<2922::AID-ANIE2922>3.0.CO
[8] 2-1
[9] Palladium-catalyzed intramolecular hydroalkylation of alkenyl-β-keto esters, α-aryl ketones, and alkyl ketones in the presence of Me3SiCl or HCl
Han, XQ
Wang, X
Pei, T
Widenhoefer, RA
[J]. CHEMISTRY-A EUROPEAN JOURNAL, 2004, 10 (24) : 6333 - 6342
[10] Gold(I)-catalyzed intramolecular hydroamination of alkenyl carbamates
Han, XQ
Widenhoefer, RA
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (11) : 1747 - 1749

← 1 2 3 4 5 →