Measurement of enantiomeric excess using molecularly imprinted polymers

被引：21

作者：

Chen, YZ ^{[1
]}

Shimizu, KD ^{[1
]}

机构：

[1] Univ S Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 17期

关键词：

D O I：

10.1021/ol026336q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method is presented for the measurement of enantiomeric excess (ee) utilizing molecularly imprinted polymers (MIPs). The method is demonstrated to be accurate and rapid, as the ee values can be calculated from straightforward concentration measurements. The MIP-based assay can also be adapted to measure the ee of samples of differing initial concentrations.

引用

页码：2937 / 2940

页数：4

共 41 条

[21]

2-7

[22]

Reetz MT, 2001, ANGEW CHEM INT EDIT, V40, P284, DOI 10.1002/1521-3773(20010119)40:2<284::AID-ANIE284>3.0.CO

[23]

2-N

[24]

Reetz MT, 2000, CHIRALITY, V12, P479, DOI 10.1002/(SICI)1520-636X(2000)12:5/6<479::AID-CHIR32>3.3.CO

[25]

2-R

[26] Creation of enantioselective biocatalysts for organic chemistry by in vitro evolution [J].

Reetz, MT ;

Zonta, A ;

Schimossek, K ;

Liebeton, K ;

Jaeger, KE .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1997, 36 (24) :2830-2832

[27] 2,15-dihydroxy-hexahelicene (HELIXOL): synthesis and use as an enantioselective fluorescent sensor [J].

Reetz, MT ;

Sostmann, S .

TETRAHEDRON, 2001, 57 (13) :2515-2520

[28]

Reetz MT, 1999, ANGEW CHEM INT EDIT, V38, P1758, DOI 10.1002/(SICI)1521-3773(19990614)38:12<1758::AID-ANIE1758>3.0.CO

[29]

2-8

[30]

Reetz MT, 1998, ANGEW CHEM INT EDIT, V37, P2647, DOI 10.1002/(SICI)1521-3773(19981016)37:19<2647::AID-ANIE2647>3.0.CO

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