A New Two-Photon-Sensitive Block Copolymer Nanocarrier

被引：255

作者：

Babin, Jerome ^{[4
]}

Pelletier, Maxime ^{[4
]}

Lepage, Martin ^{[2
,3
]}

Allard, Jean-Francois ^{[1
]}

Morris, Denis ^{[1
]}

Zhao, Yue ^{[4
]}

机构：

[1] Univ Sherbrooke, Dept Phys, Sherbrooke, PQ J1K 2R1, Canada

[2] Univ Sherbrooke, Dept Med Nucl & Radiobiol, Sherbrooke, PQ J1K 2R1, Canada

[3] Univ Sherbrooke, Ctr Imagerie Mol Sherbrooke, Sherbrooke, PQ J1K 2R1, Canada

[4] Univ Sherbrooke, Dept Chem, Sherbrooke, PQ J1K 2R1, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 18期

基金：

加拿大自然科学与工程研究理事会;

关键词：

block copolymers; dyes and pigments; micelles; photochemistry; photocontrollable release; SUPRAMOLECULAR ASSEMBLIES; POLYMERIC MICELLES; DRUG-DELIVERY; VESICLES; LIGHT; RELEASE; DESIGN; MICELLIZATION; NANOPARTICLES;

D O I：

10.1002/anie.200900255

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Easily disrupted: Micelles of a new amphiphilic block copolymer that bear coumarin groups are sensitive to near infrared light by two-photon absorption of the chromophore. Disruption of the micelles under irradiation at 794 nm results in release of both photocleaved coumarin and encapsulated nile red from the hydrophobic core of micelle into aqueous solution, which results in opposing changes in fluorescence emission intensity. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3329 / 3332

页数：4

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