A New Two-Photon-Sensitive Block Copolymer Nanocarrier

被引:255
作者
Babin, Jerome [4 ]
Pelletier, Maxime [4 ]
Lepage, Martin [2 ,3 ]
Allard, Jean-Francois [1 ]
Morris, Denis [1 ]
Zhao, Yue [4 ]
机构
[1] Univ Sherbrooke, Dept Phys, Sherbrooke, PQ J1K 2R1, Canada
[2] Univ Sherbrooke, Dept Med Nucl & Radiobiol, Sherbrooke, PQ J1K 2R1, Canada
[3] Univ Sherbrooke, Ctr Imagerie Mol Sherbrooke, Sherbrooke, PQ J1K 2R1, Canada
[4] Univ Sherbrooke, Dept Chem, Sherbrooke, PQ J1K 2R1, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
block copolymers; dyes and pigments; micelles; photochemistry; photocontrollable release; SUPRAMOLECULAR ASSEMBLIES; POLYMERIC MICELLES; DRUG-DELIVERY; VESICLES; LIGHT; RELEASE; DESIGN; MICELLIZATION; NANOPARTICLES;
D O I
10.1002/anie.200900255
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Easily disrupted: Micelles of a new amphiphilic block copolymer that bear coumarin groups are sensitive to near infrared light by two-photon absorption of the chromophore. Disruption of the micelles under irradiation at 794 nm results in release of both photocleaved coumarin and encapsulated nile red from the hydrophobic core of micelle into aqueous solution, which results in opposing changes in fluorescence emission intensity. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:3329 / 3332
页数:4
相关论文
共 31 条
[11]   Coumarinylmethyl esters for ultrafast release of high concentrations of cyclic nucleotides upon one- and two-photon photolysis [J].
Hagen, V ;
Dekowski, B ;
Nache, V ;
Schmidt, R ;
Geissler, D ;
Lorenz, D ;
Eichhorst, J ;
Keller, S ;
Kaneko, H ;
Benndorf, K ;
Wiesner, B .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (48) :7887-7891
[12]   Reversible Photocontrolled Swelling-Shrinking Behavior of Micron Vesicles Self-Assembled from Azopyridine-Containing Diblock Copolymer [J].
Han, Kuo ;
Su, Wei ;
Zhong, Mincheng ;
Yan, Qing ;
Luo, Yanhua ;
Zhang, Qijin ;
Li, Yinmei .
MACROMOLECULAR RAPID COMMUNICATIONS, 2008, 29 (23) :1866-1870
[13]   Polymer micelles stabilization on demand through reversible photo-cross-linking [J].
Jiang, Jinqiang ;
Qi, Bo ;
Lepage, Martin ;
Zhao, Yue .
MACROMOLECULES, 2007, 40 (04) :790-792
[14]   Toward photocontrolled release using light-dissociable block copolymer micelles [J].
Jiang, JQ ;
Tong, X ;
Morris, D ;
Zhao, Y .
MACROMOLECULES, 2006, 39 (13) :4633-4640
[15]   A new design for light-breakable polymer micelles [J].
Jiang, JQ ;
Tong, X ;
Zhao, Y .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (23) :8290-8291
[16]   Multiple micellization and dissociation transitions of thermo- and light-sensitive poly(ethylene oxide)-b-poly(ethoxytri(ethylene glycol) acrylate-co-o-nitrobenzyl acrylate) in water [J].
Jiang, Xueguang ;
Lavender, Christopher A. ;
Woodcock, Jeremiah W. ;
Zhao, Bin .
MACROMOLECULES, 2008, 41 (07) :2632-2643
[17]  
Lee H., 2007, ANGEW CHEM, V119, P2505, DOI DOI 10.1002/(ISSN)1521-3757
[18]   Light-induced reversible formation of polymeric micelles [J].
Lee, Hyung-il ;
Wu, Wei ;
Oh, Jung Kwon ;
Mueller, Laura ;
Sherwood, Gizelle ;
Peteanu, Linda ;
Kowalewski, Tomasz ;
Matyjaszewski, Krzysztof .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (14) :2453-2457
[19]   pH-responsive shell cross-linked nanoparticles with hydrolytically labile cross-links [J].
Li, Yali ;
Du, Wenjun ;
Sun, Guorong ;
Wooley, Karen L. .
MACROMOLECULES, 2008, 41 (18) :6605-6607
[20]   Cucurbit[10]uril [J].
Liu, SM ;
Zavalij, PY ;
Isaacs, L .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (48) :16798-16799