Reliability of Corneal Dynamic Scheimpflug Analyser Measurements in Virgin and Post-PRK Eyes

Purpose: To determine the measurement reliability of CorVis ST, a dynamic Scheimpflug analyser, in virgin and postphotorefractive keratectomy (PRK) eyes and compare the results between these two groups. Methods: Forty virgin eyes and 42 post-PRK eyes underwent CorVis ST measurements performed by two technicians. Repeatability was evaluated by comparing three consecutive measurements by technician A. Reproducibility was determined by comparing the first measurement by technician A with one performed by technician B. Intraobserver and interobserver intraclass correlation coefficients (IC(s) were calculated. Univariate analysis of covariance (ANCOVA) was used to compare measured parameters between virgin and post-PRK eyes. Results: The intraocular pressure (IOP), central corneal thickness (CCT) and 1st applanation time demonstrated good intraobserver repeatability and interobserver reproducibility (ICC >= 0.90) in virgin and post-PRK eyes. The deformation amplitude showed a good or close to good repeatability and reproducibility in both groups (ICC >= 0.88). The (CT correlated positively with 1st applanation time (r 0.437 and 0.483, respectively, p<0.05) and negatively with deformation amplitude (r = -0.384 and -0.375, respectively, p<0.05) in both groups. Compared to post-PRK eyes, virgin eyes showed longer 1st applanation time (7.29 +/- 0.21 vs. 6.96 +/- 0.17 ms, p<0.05) and lower deformation amplitude (1.06 +/- 0.07 vs. 1.17 +/- 0.08 mm, p<0.05). Conclusions: CorVis ST demonstrated reliable measurements for CCT, IOP, and 1st applanation time, as well as relatively reliable measurement for deformation amplitude in both virgin and post-PRK eyes. There were differences in 1st applanation time and deformation amplitude between virgin and post-PRK eyes, which may reflect corneal biomechanical changes occurring after the surgery in the latter.