An unusual non-radical phenolic coupling

被引：6

作者：

Bell, NV

Bowman, WR

Coe, PF

Turner, AT

Whybrow, D

机构：

[1] LOUGHBOROUGH UNIV TECHNOL, DEPT CHEM, LOUGHBOROUGH LE11 3TU, LEICS, ENGLAND

[2] KNOLL PHARMACEUT, CHEM DEV GRP, NOTTINGHAM NG1 1GF, ENGLAND

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 14期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(97)00407-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Substituted-2,6-diiodophenols undergo non-radical ortho-ortho phenolic coupling by an S(N)2 mechanism with liberation of I-2 to yield the corresponding biphenyls. in particular, the ethyl ester of N-acetyl-3,5-diiodotyrosine gives good yields of the corresponding dityrosine analogue 2 under mild conditions. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：2581 / 2584

页数：4

共 16 条

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