Novel simple and highly modular ligands for efficient asymmetric transfer-hydrogenation of ketones

被引:64
作者
Pastor, IM [1 ]
Västilä, P [1 ]
Adolfsson, H [1 ]
机构
[1] Stockholm Univ, Dept Organ Chem, SE-10691 Stockholm, Sweden
关键词
D O I
10.1039/b206471e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Novel simple and highly modular dipeptide-analogue ligands combined with [RuCl2(p-cymene)](2) were demonstrated to efficiently catalyze the reduction of ketones under hydrogen transfer conditions with enantioselectivities up to 96%.
引用
收藏
页码:2046 / 2047
页数:2
相关论文
共 10 条
[1]  
Carmona D, 1999, CHEM-EUR J, V5, P1544, DOI 10.1002/(SICI)1521-3765(19990503)5:5<1544::AID-CHEM1544>3.3.CO
[2]  
2-K
[3]   Catalysts for the asymmetric transfer hydrogenation of ketones derived from L-prolinamide and (p-cymeneRuCl2)2 or (Cp*RhCl2)2 [J].
Faller, JW ;
Lavoie, AR .
ORGANOMETALLICS, 2001, 20 (24) :5245-5247
[4]   Enantioselective hydride transfer hydrogenation of ketones catalyzed by [(η6-p-cymene)Ru(amino acidato)Cl] and [(η6-p-cymene)Ru(amino acidato)]3(BF4)3 complexes [J].
Kathó, A ;
Carmona, D ;
Viguri, F ;
Remacha, CD ;
Kovács, J ;
Joó, F ;
Oro, LA .
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2000, 593 :299-306
[5]   Asymmetric transfer hydrogenation catalyzed by chiral ruthenium complexes [J].
Noyori, R ;
Hashiguchi, S .
ACCOUNTS OF CHEMICAL RESEARCH, 1997, 30 (02) :97-102
[6]   α-Amino acid:: an effective ligand for asymmetric catalysis of transfer hydrogenation of ketones [J].
Ohta, T ;
Nakahara, S ;
Shigemura, Y ;
Hattori, K ;
Furukawa, I .
APPLIED ORGANOMETALLIC CHEMISTRY, 2001, 15 (08) :699-709
[7]   Novel highly modular C2-symmetric oxazoline ligands-application in titanium-catalyzed diethylzinc additions to aldehydes [J].
Pastor, IM ;
Adolfsson, H .
TETRAHEDRON LETTERS, 2002, 43 (09) :1743-1746
[8]   The first Ru(II)-catalysed asymmetric hydrogen transfer reduction of aromatic ketones in aqueous media [J].
Rhyoo, HY ;
Park, HJ ;
Chung, YK .
CHEMICAL COMMUNICATIONS, 2001, (20) :2064-2065
[9]   Use of amino amides derived from proline as chiral ligands in the ruthenium(II)-catalyzed transfer hydrogenation reaction of ketones [J].
Rhyoo, HY ;
Yoon, YA ;
Park, HJ ;
Chung, YK .
TETRAHEDRON LETTERS, 2001, 42 (30) :5045-5048
[10]   Amino alcohol effects on the ruthenium(II)-catalysed asymmetric transfer hydrogenation of ketones in propan-2-ol [J].
Takehara, J ;
Hashiguchi, S ;
Fujii, A ;
Inoue, S ;
Ikariya, T ;
Noyori, R .
CHEMICAL COMMUNICATIONS, 1996, (02) :233-234