Multi-channel time-resolved system for functional near infrared spectroscopy

被引:95
作者
Contini, Davide [1 ]
Torricelli, Alessandro
Pifferi, Antonio
Spinelli, Lorenzo
Paglia, Floriano
Cubeddu, Rinaldo
机构
[1] Politecn Milan, ULTRAS, CNR, INFM,Dipartimento Fis, I-20133 Milan, Italy
[2] Politecn Milan, CNR, IFN, Dipartimento Fis, I-20133 Milan, Italy
关键词
D O I
10.1364/OE.14.005418
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We have designed a compact dual wavelength multi-channel time-resolved system for functional near infrared spectroscopy. The system enables 16 sources and up to 64 collection points, with a minimum acquisition time of 5 ms per channel. Performances of the system have been tested on tissue phantoms in terms of linearity, noise, stability and reproducibility. Preliminary measurements on volunteers have been performed to validate the instrument capability to acquire in vivo maps of the hemodynamic parameters in the muscle during arterial occlusion and in the adult head during a finger tapping experiment. (c) 2006 Optical Society of America.
引用
收藏
页码:5418 / 5432
页数:15
相关论文
共 37 条
[1]   Time and wavelength resolved spectroscopy of turbid media using light continuum generated in a crystal fiber [J].
Abrahamsson, C ;
Svensson, T ;
Svanberg, S ;
Andersson-Engels, S ;
Johansson, J ;
Folestad, S .
OPTICS EXPRESS, 2004, 12 (17) :4103-4112
[2]  
Becker W., 2005, ADV TIME CORRELATED
[3]   Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy [J].
Boas, DA ;
Dale, AM ;
Franceschini, MA .
NEUROIMAGE, 2004, 23 :S275-S288
[4]   Multichannel time-resolved tissue oximeter for functional imaging of the brain [J].
Contini, D ;
Torricelli, A ;
Pifferi, A ;
Spinelli, L ;
Taroni, P ;
Quaresima, V ;
Ferrari, M ;
Cubeddu, R .
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2006, 55 (01) :85-90
[5]   Experimental test of theoretical models for time-resolved reflectance [J].
Cubeddu, R ;
Pifferi, A ;
Taroni, P ;
Torricelli, A ;
Valentini, G .
MEDICAL PHYSICS, 1996, 23 (09) :1625-1633
[6]   Compact tissue oximeter based on dual-wavelength multichannel time-resolved reflectance [J].
Cubeddu, R ;
Pifferi, A ;
Taroni, P ;
Torricelli, A ;
Valentini, G .
APPLIED OPTICS, 1999, 38 (16) :3670-3680
[7]   Time-resolved optical imaging through turbid media using a fast data acquisition system based on a gated CCD camera [J].
D'Andrea, C ;
Comelli, D ;
Pifferi, A ;
Torricelli, A ;
Valentini, G ;
Cubeddu, R .
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2003, 36 (14) :1675-1681
[8]   Penetration depth of light re-emitted by a diffusive medium: theoretical and experimental investigation [J].
Del Bianco, S ;
Martelli, F ;
Zaccanti, G .
PHYSICS IN MEDICINE AND BIOLOGY, 2002, 47 (23) :4131-4144
[9]   A perturbation approach to characterize absorptive inclusions in media by time-resolved contrast measurements [J].
Esposito, R ;
De Nicola, S ;
Lepore, M ;
Delfino, I ;
Indovina, PL .
JOURNAL OF OPTICS A-PURE AND APPLIED OPTICS, 2004, 6 (07) :736-741
[10]   BOUNDARY-CONDITIONS FOR THE DIFFUSION EQUATION IN RADIATIVE-TRANSFER [J].
HASKELL, RC ;
SVAASAND, LO ;
TSAY, TT ;
FENG, TC ;
MCADAMS, MS ;
TROMBERG, BJ .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1994, 11 (10) :2727-2741