Fluoroquinolone-resistant Streptococcus pneumoniae strains occur frequently in elderly patients in Japan

被引：35

作者：

Yokota, S

Sato, K

Kuwahara, O

Habadera, S

Tsukamoto, N

Ohuchi, H

Akizawa, H

Himi, T

Fujii, N

机构：

[1] Sapporo Med Univ, Sch Med, Dept Microbiol, Chuo Ku, Sapporo, Hokkaido 0608556, Japan

[2] Sapporo Med Univ, Sch Med, Dept Otolaryngol, Chuo Ku, Sapporo, Hokkaido 0608556, Japan

[3] Wako Junyaku Co Ltd, Kita Ku, Sapporo, Hokkaido 0010015, Japan

[4] Sapporo Clin Lab Inc, Chuo Ku, Sapporo, Hokkaido 0600005, Japan

[5] SRL Hokkaido Inc, Chuo Ku, Sapporo, Hokkaido 0640919, Japan

[6] Hokkaido Univ, Hosp Med, Lab Med, Kita Ku, Sapporo, Hokkaido 0608648, Japan

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 10期

关键词：

D O I：

10.1128/AAC.46.10.3311-3315.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We identified and genetically characterized seven fluoroquinolone-resistant Streptococcus pneumoniae strains among 293 clinical strains isolated from 1999 to 2001 in Japan. The resistant strains were isolated only from adults, and 7 of 31 isolates (22.6%) were from patients more than 20 years old. Resistant strains were not found in 262 isolates from children under age 10.

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页码：3311 / 3315

页数：5

相关论文

共 27 条

[1] Molecular characterization of the gene encoding the DNA gyrase a subunit of Streptococcus pneumoniae [J].

Balas, D ;

Fernández-Moreira, E ;

De la Campa, AG .

JOURNAL OF BACTERIOLOGY, 1998, 180 (11) :2854-2861

[2] Fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae:: Contributions of type II topoisomerase mutations and efflux to levels of resistance [J].

Bast, DJ ;

Low, DE ;

Duncan, CL ;

Kilburn, L ;

Mandell, LA ;

Davidson, RJ ;

de Azavedo, JCS .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (11) :3049-3054

[3] Interspecies recombination contributes minimally to fluoroquinolone resistance in Streptococcus pneumoniae [J].

Bast, DJ ;

de Azavedo, JCS ;

Tam, TY ;

Kilburn, L ;

Duncan, C ;

Mandell, LA ;

Davidson, RJ ;

Low, DE .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (09) :2631-2634

[4] A convenient assay for estimating the possible involvement of efflux of fluoroquinolones by Streptococcus pneumoniae and Staphylococcus aureus:: Evidence for diminished moxifloxacin, sparfloxacin, and trovafloxacin efflux [J].

Beyer, R ;

Pestova, E ;

Millichap, JJ ;

Stosor, V ;

Noskin, GA ;

Peterson, LR .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (03) :798-801

[5] Prevalence of a putative efflux mechanism among fluoroquinolone-resistant clinical isolates of Streptococcus pneumoniae [J].

Brenwald, NP ;

Gill, MJ ;

Wise, R .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (08) :2032-2035

[6] Efflux and target mutations as quinolone resistance mechanisms in clinical isolates of Streptococcus pneumoniae [J].

Broskey, J ;

Coleman, K ;

Gwynn, MN ;

McCloskey, L ;

Traini, C ;

Voelker, L ;

Warren, R .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 45 :95-99

[7] Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada [J].

Chen, DK ;

McGeer, A ;

de Azavedo, JC ;

Low, DE .

NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (04) :233-239

[8] Nasopharyngeal carriage of antimicrobial-resistant Streptococcus pneumoniae among young children attending 79 kindergartens and day care centers in Hong Kong [J].

Chiu, SS ;

Ho, PL ;

Chow, FKH ;

Yuen, KY ;

Lau, YL .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (10) :2765-2770

[9] Activities of newer fluoroquinolones against ciprofloxacin resistant Streptococcus pneumoniae [J].

Coyle, EA ;

Kaatz, GW ;

Rybak, MJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (06) :1654-1659

[10] Trends in the antimicrobial susceptibility of bacterial respiratory tract pathogens - Findings of the Alexander Project 1992-1996 [J].

Felmingham, D ;

Washington, J .

JOURNAL OF CHEMOTHERAPY, 1999, 11 :5-21