Total synthesis of the virginiamycin antibiotic 14,15-anhydropristinamycin IIB

被引：26

作者：

Entwistle, DA ^{[1
]}

Jordan, SI ^{[1
]}

Montgomery, J ^{[1
]}

Pattenden, G ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 12期

关键词：

D O I：

10.1039/p19960001315

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A total synthesis of the virginiamycin 14,15-anhydro-pristinamycin IIB 16 has been achieved from chiral, nonracemic starling materials, and using a route which features an intramolecular Stille coupling reaction, viz. 14-->15, as the key stratagem. The virginiamycin 16 was identical with an authentic sample produced from a Streptomyces fermentation process.

引用

页码：1315 / 1317

页数：3

共 42 条

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