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Protein folding - Inside the cage
被引:19
作者
:
Ellis, R. John
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Warwick, Dept Biol Sci, Coventry CV4 7AL, W Midlands, England
Univ Warwick, Dept Biol Sci, Coventry CV4 7AL, W Midlands, England
Ellis, R. John
[
1
]
机构
:
[1]
Univ Warwick, Dept Biol Sci, Coventry CV4 7AL, W Midlands, England
来源
:
NATURE
|
2006年
/ 442卷
/ 7101期
关键词
:
D O I
:
10.1038/442360a
中图分类号
:
O [数理科学和化学];
P [天文学、地球科学];
Q [生物科学];
N [自然科学总论];
学科分类号
:
07 ;
0710 ;
09 ;
摘要
:
Many newly synthesized bacterial proteins avoid aggregation by folding inside a chaperonin nanocage. Unexpectedly, it turns out that the cage's internal properties can be optimized to accelerate folding.
引用
收藏
页码:360 / 362
页数:3
相关论文
共 10 条
[1]
Dual function of protein confinement in chaperonin-assisted protein folding
[J].
Brinker, A
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Brinker, A
;
Pfeifer, G
论文数:
0
引用数:
0
h-index:
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Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Pfeifer, G
;
Kerner, MJ
论文数:
0
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0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Kerner, MJ
;
Naylor, DJ
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Naylor, DJ
;
Hartl, FU
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0
h-index:
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Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Hartl, FU
;
Hayer-Hartl, M
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Hayer-Hartl, M
.
CELL,
2001,
107
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:223
-233
[2]
Protein aggregation in crowded environments
[J].
Ellis, R. John
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Warwick, Dept Sci Biol, Coventry CV4 7AL, W Midlands, England
Univ Warwick, Dept Sci Biol, Coventry CV4 7AL, W Midlands, England
Ellis, R. John
;
Minton, Allen P.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Warwick, Dept Sci Biol, Coventry CV4 7AL, W Midlands, England
Minton, Allen P.
.
BIOLOGICAL CHEMISTRY,
2006,
387
(05)
:485
-497
[3]
Ellis R. John, 2005, P3, DOI 10.1017/CBO9780511546310.002
[4]
Revisiting the Anfinsen cage
[J].
Ellis, RJ
论文数:
0
引用数:
0
h-index:
0
机构:
Department of Biological Sciences, University of Warwick
Ellis, RJ
.
FOLDING & DESIGN,
1996,
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[5]
Chaperonin-mediated protein folding: fate of substrate polypeptide
[J].
Fenton, WA
论文数:
0
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0
h-index:
0
机构:
Yale Univ, Sch Med, Dept Genet, New Haven, CT 06510 USA
Fenton, WA
;
Horwich, AL
论文数:
0
引用数:
0
h-index:
0
机构:
Yale Univ, Sch Med, Dept Genet, New Haven, CT 06510 USA
Horwich, AL
.
QUARTERLY REVIEWS OF BIOPHYSICS,
2003,
36
(02)
:229
-256
[6]
Proteome-wide analysis of chaperonin-dependent protein folding in Escherichia coli
[J].
Kerner, MJ
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Kerner, MJ
;
Naylor, DJ
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0
引用数:
0
h-index:
0
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Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Naylor, DJ
;
Ishihama, Y
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0
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0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Ishihama, Y
;
Maier, T
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0
引用数:
0
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Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
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Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Chang, HC
;
Stines, AP
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0
引用数:
0
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0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Stines, AP
;
Georgopoulos, C
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Georgopoulos, C
;
Frishman, D
论文数:
0
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0
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Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Frishman, D
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Hayer-Hartl, M
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0
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0
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Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Hayer-Hartl, M
;
Mann, M
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0
引用数:
0
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0
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Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Mann, M
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Hartl, FU
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Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Hartl, FU
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CELL,
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The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media
[J].
Minton, AP
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机构:
NIDDK, Sect Phys Biochem, Lab Biochem & Genet, NIH, Bethesda, MD 20892 USA
NIDDK, Sect Phys Biochem, Lab Biochem & Genet, NIH, Bethesda, MD 20892 USA
Minton, AP
.
JOURNAL OF BIOLOGICAL CHEMISTRY,
2001,
276
(14)
:10577
-10580
[8]
The chaperonin folding machine
[J].
Saibil, HR
论文数:
0
引用数:
0
h-index:
0
机构:
Univ London Birkbeck Coll, Sch Crystallog, London WC1E 7HX, England
Saibil, HR
;
Ranson, NA
论文数:
0
引用数:
0
h-index:
0
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Univ London Birkbeck Coll, Sch Crystallog, London WC1E 7HX, England
Ranson, NA
.
TRENDS IN BIOCHEMICAL SCIENCES,
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(12)
:627
-632
[9]
Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein
[J].
Tang, Yun-Chi
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0
引用数:
0
h-index:
0
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Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
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Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
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0
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0
h-index:
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Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
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CELL,
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125
(05)
:903
-914
[10]
The crystal structure of the asymmetric GroEL-GroES-(ADP)(7) chaperonin complex
[J].
Xu, ZH
论文数:
0
引用数:
0
h-index:
0
机构:
YALE UNIV,DEPT MOL BIOPHYS & BIOCHEM,NEW HAVEN,CT 06510
Xu, ZH
;
Horwich, AL
论文数:
0
引用数:
0
h-index:
0
机构:
YALE UNIV,DEPT MOL BIOPHYS & BIOCHEM,NEW HAVEN,CT 06510
Horwich, AL
;
Sigler, PB
论文数:
0
引用数:
0
h-index:
0
机构:
YALE UNIV,DEPT MOL BIOPHYS & BIOCHEM,NEW HAVEN,CT 06510
Sigler, PB
.
NATURE,
1997,
388
(6644)
:741
-750
←
1
→
共 10 条
[1]
Dual function of protein confinement in chaperonin-assisted protein folding
[J].
Brinker, A
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Brinker, A
;
Pfeifer, G
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Pfeifer, G
;
Kerner, MJ
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Kerner, MJ
;
Naylor, DJ
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Naylor, DJ
;
Hartl, FU
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Hartl, FU
;
Hayer-Hartl, M
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Hayer-Hartl, M
.
CELL,
2001,
107
(02)
:223
-233
[2]
Protein aggregation in crowded environments
[J].
Ellis, R. John
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Warwick, Dept Sci Biol, Coventry CV4 7AL, W Midlands, England
Univ Warwick, Dept Sci Biol, Coventry CV4 7AL, W Midlands, England
Ellis, R. John
;
Minton, Allen P.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Warwick, Dept Sci Biol, Coventry CV4 7AL, W Midlands, England
Minton, Allen P.
.
BIOLOGICAL CHEMISTRY,
2006,
387
(05)
:485
-497
[3]
Ellis R. John, 2005, P3, DOI 10.1017/CBO9780511546310.002
[4]
Revisiting the Anfinsen cage
[J].
Ellis, RJ
论文数:
0
引用数:
0
h-index:
0
机构:
Department of Biological Sciences, University of Warwick
Ellis, RJ
.
FOLDING & DESIGN,
1996,
1
(01)
:R9
-R15
[5]
Chaperonin-mediated protein folding: fate of substrate polypeptide
[J].
Fenton, WA
论文数:
0
引用数:
0
h-index:
0
机构:
Yale Univ, Sch Med, Dept Genet, New Haven, CT 06510 USA
Fenton, WA
;
Horwich, AL
论文数:
0
引用数:
0
h-index:
0
机构:
Yale Univ, Sch Med, Dept Genet, New Haven, CT 06510 USA
Horwich, AL
.
QUARTERLY REVIEWS OF BIOPHYSICS,
2003,
36
(02)
:229
-256
[6]
Proteome-wide analysis of chaperonin-dependent protein folding in Escherichia coli
[J].
Kerner, MJ
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Kerner, MJ
;
Naylor, DJ
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Naylor, DJ
;
Ishihama, Y
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Ishihama, Y
;
Maier, T
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Maier, T
;
Chang, HC
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Chang, HC
;
Stines, AP
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Stines, AP
;
Georgopoulos, C
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Georgopoulos, C
;
Frishman, D
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Frishman, D
;
Hayer-Hartl, M
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Hayer-Hartl, M
;
Mann, M
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Mann, M
;
Hartl, FU
论文数:
0
引用数:
0
h-index:
0
机构:
Max Planck Inst Biochem, Dept Cellular Biochem, D-82152 Martinsried, Germany
Hartl, FU
.
CELL,
2005,
122
(02)
:209
-220
[7]
The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media
[J].
Minton, AP
论文数:
0
引用数:
0
h-index:
0
机构:
NIDDK, Sect Phys Biochem, Lab Biochem & Genet, NIH, Bethesda, MD 20892 USA
NIDDK, Sect Phys Biochem, Lab Biochem & Genet, NIH, Bethesda, MD 20892 USA
Minton, AP
.
JOURNAL OF BIOLOGICAL CHEMISTRY,
2001,
276
(14)
:10577
-10580
[8]
The chaperonin folding machine
[J].
Saibil, HR
论文数:
0
引用数:
0
h-index:
0
机构:
Univ London Birkbeck Coll, Sch Crystallog, London WC1E 7HX, England
Saibil, HR
;
Ranson, NA
论文数:
0
引用数:
0
h-index:
0
机构:
Univ London Birkbeck Coll, Sch Crystallog, London WC1E 7HX, England
Ranson, NA
.
TRENDS IN BIOCHEMICAL SCIENCES,
2002,
27
(12)
:627
-632
[9]
Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein
[J].
Tang, Yun-Chi
论文数:
0
引用数:
0
h-index:
0
机构:
Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
Tang, Yun-Chi
;
Chang, Hung-Chun
论文数:
0
引用数:
0
h-index:
0
机构:
Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
Chang, Hung-Chun
;
Roeben, Annette
论文数:
0
引用数:
0
h-index:
0
机构:
Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
Roeben, Annette
;
Wischnewski, Dirk
论文数:
0
引用数:
0
h-index:
0
机构:
Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
Wischnewski, Dirk
;
Wischnewski, Nadine
论文数:
0
引用数:
0
h-index:
0
机构:
Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
Wischnewski, Nadine
;
Kerner, Michael J.
论文数:
0
引用数:
0
h-index:
0
机构:
Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
Kerner, Michael J.
;
Hartl, F. Ulrich
论文数:
0
引用数:
0
h-index:
0
机构:
Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
Hartl, F. Ulrich
;
Hayer-Hartl, Manajit
论文数:
0
引用数:
0
h-index:
0
机构:
Tech Univ Denmark, BioCent, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark
Hayer-Hartl, Manajit
.
CELL,
2006,
125
(05)
:903
-914
[10]
The crystal structure of the asymmetric GroEL-GroES-(ADP)(7) chaperonin complex
[J].
Xu, ZH
论文数:
0
引用数:
0
h-index:
0
机构:
YALE UNIV,DEPT MOL BIOPHYS & BIOCHEM,NEW HAVEN,CT 06510
Xu, ZH
;
Horwich, AL
论文数:
0
引用数:
0
h-index:
0
机构:
YALE UNIV,DEPT MOL BIOPHYS & BIOCHEM,NEW HAVEN,CT 06510
Horwich, AL
;
Sigler, PB
论文数:
0
引用数:
0
h-index:
0
机构:
YALE UNIV,DEPT MOL BIOPHYS & BIOCHEM,NEW HAVEN,CT 06510
Sigler, PB
.
NATURE,
1997,
388
(6644)
:741
-750
←
1
→